The human cathelicidin hCAP18/LL-37 is an antimicrobial protein consisting of a conserved N-terminal prosequence called the cathelin-like domain and a C-terminal peptide called LL-37. This peptide contains 37 amino acid residues, and several truncated variants obtained from natural sources or by chemical synthesis differ in their capability to damage Gram positive and Gram negative bacteria as ...

In early development, genes are expressed in spatial patterns which later define cellular identities and tissue locations. The mechanisms of such pattern formation have been studied extensively in early Drosophila (fruit fly) embryos. The gap gene hunchback (hb) is one of the earliest genes to be expressed in anterior-posterior (AP) body segmentation. As a transcriptional regulator for a number...

Medical operation planning is a substantial element of hospital management. It is characterized by high complexity, which is caused by the uncertainty between the offered capacity and the true demand. As emergency cases occur the planning requirements will change. Therefore, the use of a dialog-based system is preferred against fully manual or fully automated systems, because of the inability o...

BACKGROUND There needs to be an amendment to the Korean version of the Alcohol Use Disorder Identification Test (AUDIT) with regards to the recent change in percent alcohol by volume (ABV) Korean liquor. This study was performed to suggest a cutoff value, reliability and validity of AUDIT-Korean revised version (AUDIT-KR), which reflect the change of the ABV of Korean alcohol. METHODS The sub...

The inflation GI of a graph G with n(G) vertices and m(G) edges is obtained from G by replacing every vertex of degree d of G by a clique, which is isomorphic to the complete graph Kd, and each edge (xi, xj) of G is replaced by an edge (u, v) in such a way that u ∈ Xi, v ∈ Xj , and two different edges of G are replaced by non-adjacent edges of GI . The total domination number γt(G) of a graph G...

Recent studies (Chiviacowsky & Wulf, 2002, 2005) have shown that learners prefer to receive feedback after they believe they had a "good" rather than "poor" trial. The present study followed up on this finding and examined whether learning would benefit if individuals received feedback after good relative to poor trials. Participants practiced a task that required them to throw beanbags at a ta...

We re-examine the fine tuning problem of the Higgs mass, when an antisymmetric two form Kalb-Ramond (KR) field is present in the bulk of a Randall-Sundrum (RS) braneworld. Taking into account the back-reaction of the KR field, we obtain the exact correction to the RS metric. The modified metric also warps the Higgs mass from Planck scale (in higher dimension) to TeV scale (on the visible brane)...

We do not know how humans reason, whether they reason using natural language (NL) or not and we are not interested in proving or disproving such a proposition. Nonetheless, it seems that a very expressive transparent medium humans communicate with, state their problems in and justify how they solve these problems is NL. Hence, we wished to use NL as a Knowledge Representation(KR) in NL knowledg...

In this study we explored the mode of action of KR-72, a 9-O-butyl-13-(4-isopropylbenzyl)berberine derivative previously shown to exhibit potent antifungal activity against a variety of human fungal pathogens. The DNA microarray data revealed that KR-72 treatment significantly changed the transcription profiles of C. neoformans, affecting the expression of more than 2,000 genes. Genes involved ...

As for a generic parameter dependent hamiltonian with the time reversal (TR) invariance, a non Abelian Berry connection with the Kramers (KR) degeneracy are introduced by using a quaternionic Berry connection. This quaternionic structure naturally extends to the many body system with the KR degeneracy. Its topological structure is explicitly discussed in comparison with the one without the KR d...