This study describes how scale-up in countercurrent chromatography (CCC) can be simply predicted on a process scale CCC device by running a preliminary analytical-sized sample and having knowledge of the stationary-phase retention at scale-up conditions. Results have shown that simple experimentation can lead within a day to a process with the capability of several kilograms per day (tons per y...

Development of CCC-NHC pincer Co complexes via transmetalation from Zr is reported. Formation of these air-stable Co(iii) complexes was achieved through use of a CoCl2 or Co(acac)3in situ or with a discrete CCC-NHC pincer Zr transmetallating agent. Preliminary activity in the hydroboration of styrene is reported. This facile methodology will further the development of CCC-NHC pincer first-row t...

A combined cell culture enzyme-linked immunosorbent assay (CCC-ELISA) was developed for measuring the neutralizing antipoliovirus antibodies in human sera. The binding of different concentrations of each of the three poliovirus types to BGM cells in the presence and absence of a constant dilution from each test and reference serum was measured in the CCC-ELISA. The titers of the viruses neutral...

We have developed a 1:30000 winding ratio cryogenic current comparator (CCC) for measurement of small currents, e.g., generated by a single electron transport device. A dedicated low-noise SQUID is used for the readout, which allows reaching a sensitivity close to ideal, that is without loss of sensitivity in the flux transformer coupling the CCC and the SQUID. The CCC-SQUID equivalent current ...

Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collagen crosslinking (CCC) using ultraviolet-A/riboflavin is effective in the treatment of bacterial k...

BACKGROUND The purpose of this study was to investigate the diagnostic value of 3.0-T (1)H magnetic resonance spectroscopy ((1)H MRS) in primary malignant hepatic tumors and to compare the effects of (1)H MRS on the diagnostic accuracy of liver-occupying lesions between junior and experienced radiologists. METHODS This study included 50 healthy volunteers and 40 consecutive patients (50 lesio...

In elderly subjects, past researches have already underlined the role of nutritional status as a basic factor able to influence the prognosis either in acute wards or in rehabilitation and long-term care settings. Aim of the study is that of retrospectively verify, through a multivariate analysis, the factors able to condition mortality in long-term care, paying particular attention to the nutr...

Prikry asked if it is relatively consistent with the usual axioms of ZFC that every nontrivial ccc forcing adds either a Cohen or a random real. Both Cohen and random reals have the property that they neither contain nor are disjoint from an infinite set of integers in the ground model, i.e. they are splitting reals. In this note I show that that it is relatively consistent with ZFC that every ...

The efficiency and robustness of reliability methods are two important factors in the first-order reliability method (FORM). The conjugate choice control (CCC) and directional chaos control method (DCC) are developed to improve the robustness and efficiency of the FORM formula using the stability transformation method. In this paper, the CCC and DCC methods are applied for the reliability analy...