In this paper, a dynamic impregnating device, which can generate supersonic vibration with the vacuum-adsorbing field, was used to prepare the hybrid graphene oxide (GO)/polyethylene glycol (PEG). Interestingly, the hybrid GO/PEG under dynamic impregnating and/or internal mixing was introduced into poly-(lactic acid) (PLA) matrix via melting-compounding, respectively. On one hand, compared with...

Polyethylene glycol (PEG 8000) is a potent cancer chemopreventive agent. This osmotic laxative polymer markedly suppresses colon cancer in rats. To explain the mechanism, we have tested the in vitro effect of PEG on four human cell lines. Two poorly differentiated adenocarcinoma lines (HT29 and COLO205), a fetal mucosa line (FHC) and a differentiated line (post-confluent Caco-2) were incubated ...

Paracellular permeability and absorptive water flux across the intestine of the euryhaline killifish were investigated using in vitro gut sac preparations from seawater- and freshwater-acclimated animals. The permeability of polyethylene glycol (PEG), a well-established paracellular probe, was measured using trace amounts of radiolabelled oligomers of three different molecular sizes (PEG-400, P...

BACKGROUND This study was performed to develop a functional poly(D,L-lactide-co-glycolide)-poly(ethylene glycol) (PLGA-PEG)-bearing amino-active end group for peptide conjugation. METHODS AND RESULTS PLGA was preactivated following by copolymerization with PEG diamine. The resulting amphiphilic PLGA-PEG copolymer bearing 97.0% of amino end groups had a critical micelle concentration of 3.0 × ...

Polyethylene glycol (PEG) was genetically incorporated into a polypeptide. Stop-anticodon-containing tRNAs were acylated with PEG-containing amino acids and were then translated into polypeptides corresponding to DNA sequences containing the stop codons. The molecular weights of the PEG used were 170, 500, 700, 1000, and 2000 Da, and the translation was confirmed by mass spectrometry. The PEG i...

the performances of two-phase polymer-liquid pebax®/polyethylene glycol (peg) and three-phase polymer-liquid-solid pebax®/peg/mwnt thin film composite membranes for co2 and ch4 permeation were studied. the effect of temperature and mwnt/pebax® ratio on single gas (co2 and ch4) permeability was investigated. the permeation of both gases was measured at different temperatures from 303 to 323 ˚k. ...

Graphene oxide (GO) is a hotspot, especially in the field of biomedical. However, the clinical application of GO is still faces a lot of challenges. In order to improve the solubility and biocompatibility of GO, polyethylene glycol (PEG) was grafted on the surface of graphene oxide by amide reaction. PEGylated graphene oxide (PEG-GO) was characterized using Fourier transform infrared spectrosco...

Competitive adsorption kinetics between thiolated polyethylene glycol (SH-PEG) and mercaptopropionic acid (MPA) on gold nanoparticles (Au-NPs) were studied using a prototype physical characterization approach that combines dynamic light scattering (DLS) and electrospray differential mobility analysis (ES-DMA). The change in hydrodynamic particle size (intensity average) due to the formation of ...

As a rare complication of percutaneous endoscopic gastroscopy (PEG), a gastrocolocutaneous fistula may occur after PEG placement. This paper reports an interesting case which PEG tube unintentionally penetrated transverse colon during PEG. A 72-year-old female patient who suffered from medullary infarction underwent PEG procedure for enteral nutrition, and fecal materials were observed 6 days a...