The role of native contact topology in the folding of a TIM barrel model based on the alpha-subunit of tryptophan synthase (alphaTS) from Salmonella typhimurium (Protein Data Bank structure 1BKS) was studied using both equilibrium and kinetic simulations. Equilibrium simulations of alphaTS reveal the population of two intermediate ensembles, I1 and I2, during unfolding/refolding at the folding ...

Proposition 0.1. Let R be a commutative ring. TFAE: 1. Every ideal in R is finitely generated. 2. Every chain of ideals I1 ⊆ I2 ⊆ · · · is stable. That is, there exists n such that In = In+1 = · · · . 3. Every nonempty set of ideals has a maximal element wrt inclusion. Proof. 1. (1) =⇒ (2). I = ⋃ k Ik ideal in R. I is generated by x1, x2, . . . xm. There exists n such that x1, . . . , xm ∈ In. ...

هدف: این تحقیق با هدف ارائه مدلی برای ارتقای صلاحیت‌های حرفه‌ای مشاوران آموزشی در خدمات به دانش‌آموزان مقطع متوسطه اول انجام شد.مواد و روش‌ها: روش پژوهش حاضر، توصیفی از نوع اکتشافی حیث رویکرد، ترکیبی (کیفی-کمی) بود. بدو کار بخش کیفی مبتنی بر اجرای مصاحبه‌های صورت نیمه‌ساختاریافته خبرگان، ابعاد مؤلفه‌ها شناسایی کمی بهره‌گیری پرسشنامه، نسبت جمع‌آوری داده‌ها اقدام شد. مشارکت‌کنندگان 14 خبره حوزه م...

Let e1, e2, . . . , en denote the standard orthogonal basis of R. Suppose that Λ Λ R is the linear space of all l-vectors, spanned by the exterior product eI ei1∧ei2∧· · ·∧eil corresponding to all ordered l-tuples I i1, i2, . . . , il , 1 ≤ i1 < i2 < · · · < il ≤ n. Throughout this paper, we always assume that Ω is an open subset of R. We use D′ M,Λ to denote the space of all differential l-for...

An [n, k, r]-hypergraph is a hypergraph :Yf = (V, E) whose vertex set V is partitioned into n k-element sets V1, V2, ... , Vn and for which, for each choice of r indices, 1 :::;; i1 < i2 < ... < ir :::;; n, there is exactly one edge e E E such that len Vii = 1 if i E {i1, i2, ... , ir} and otherwise le n Vii = 0. An independent transversal of an [n, k, r ]-hypergraph is a set T = {a1,a2, .. . ,...

Let K be a class of algebras. A0 ∈ K is in the amalgamation base of K, briefly A0 ∈ APbase(K), if for all A1,A2 ∈ K and monomorphisms i1 : A0 → A1 i2 : A0 → A2 there exist D ∈ K and monomorphisms m1 : A1 → D and m2 : A2 → D such that m1 ◦ i1 = m2 ◦ i2. CAα stands for the class of cylindric algebras of dimension α. We determine the amalgamation base for the class of representable CAα’s (RCAα). W...

We present a generalization of the classical Schur modules of GL(N) exhibiting the same interplay among algebra, geometry, and combinatorics. A generalized Young diagram D is an arbitrary finite subset of N × N. For each D, we define the Schur module SD of GL(N). We introduce a projective variety FD and a line bundle LD, and describe the Schur module in terms of sections of LD. For diagrams wit...

In this paper we present an algorithm that generates k-noncrossing, σ-modular diagrams with uniform probability. A diagram is a labeled graph of degree ≤ 1 over n vertices drawn in a horizontal line with arcs (i, j) in the upper half-plane. A k-crossing in a diagram is a set of k distinct arcs (i1, j1), (i2, j2), . . . , (ik, jk) with the property i1 < i2 < . . . < ik < j1 < j2 < . . . < jk. A ...

شرایط افروزش و اشتعال سوخت‌های گداخت هسته‌ای در حضور ناخالص­‌ها، یکی از موارد مهمی است که طراحی قرص‌های سوخت باید مورد توجه قرار گیرد. این مقاله اثر ناخالصی هسته سنگین طلا بر کلیه فرایندهای احتراق پلاسمای غیرتعادلی دوتریم- تریتیم مدل چهار دمایی آن شکل تابع توزیع انرژی رفتار فوتون‌ها تأثیر می‌گذارد بررسی گرفته است. مطالعه شامل اثرات منفی سوخت، طول زمان تشکیل لکه داغ نتایج محاسبات عددی به­ دست آم...

The present study was undertaken to investigate the sedative, analgesic and clinical effects of xylazine, medetomidine and dexmedetomidine with fentanyl as pre-anaesthetics in water buffaloes and to compare the dose-sparing effect of xylazine, medetomidine and dexmedetomidine on thiopental for induction and isoflurane for maintenance of anaesthesia in water buffaloes. Six male water buffaloes r...