Kalhorn, Thomas, and Richard A. Zager. Renal cortical ceramide patterns during ischemic and toxic injury: assessments by HPLC-mass spectrometry. Am. J. Physiol. 277 (Renal Physiol. 46): F723–F733, 1999.—Ceramides are a class of signaling molecules that can acutely accumulate in tissues as part of a ‘‘stress response.’’ They are classically measured by the diacylglycerol kinase assay, which, in ...

Choudhry, Mashkoor A., Philip E. Hockberger, and Mohammed M. Sayeed. PGE2 suppresses mitogen-induced Ca21 mobilization in T cells. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1741–R1748, 1999.—PGE2mediated suppression of T cell proliferation during sepsis could result from altered Ca21 signaling. The present study evaluated the effects of PGE2 on Ca21 release from intracell...

Hines, Wirt A., Jacqueline Thorburn, and Andrew Thorburn. Cell density and contraction regulate p38 MAP kinase-dependent responses in neonatal rat cardiac myocytes. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H331– H341, 1999.—In vitro cardiac myocyte hypertrophy is characterized by increased cell size, sarcomere organization, and induction of several genes including atrial natriuretic facto...

Pflueger, Axel C., Timothy S. Larson, Siegfried Hagl, and Franklyn G. Knox. Role of nitric oxide in intrarenal hemodynamics in experimental diabetes mellitus in rats. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R725–R733, 1999.—The role of nitric oxide (NO) in the regulation of the intrarenal microcirculation in streptozotocin (STZ)-induced diabetes mellitus in rats is not c...

Schwartz, Gary J., Andrew Whitney, Chris Skoglund, Thomas W. Castonguay and Timothy H. Moran. Decreased responsiveness to dietary fat in Otsuka Long-Evans Tokushima fatty rats lacking CCK-Areceptors. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1144– R1151, 1999.—Adult Otsuka Long-Evans Tokushima fatty (OLETF) rats lack functional cholecystokinin A (CCK-A) receptors, are dia...

Korthuis, Ronald J., Dean C. Gute, Frank Blecha, and Chris R. Ross. PR-39, a proline/arginine-rich antimicrobial peptide, prevents postischemic microvascular dysfunction. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1007– H1013, 1999.—We and others have previously demonstrated that intestinal ischemia-reperfusion (I/R) is associated with a large increase in oxidant production that contribute...

Rinaman, Linda. Interoceptive stress activates glucagonlike peptide-1 neurons that project to the hypothalamus. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R582–R590, 1999.—This study tested the hypothesis that systemic stressors in rats activate glucagon-like peptide-1 (GLP-1)-immunoreactive neurons in the caudal brain stem, including those that project to the paraventricul...

Tonkonogi, M., and K. Sahlin. Actively phosphorylating mitochondria are more resistant to lactic acidosis than inactive mitochondria. Am. J. Physiol. 277 (Cell Physiol. 46): C288–C293, 1999.—Oxidative phosphorylation of isolated rat skeletal muscle mitochondria after exposure to lactic acidosis in either phosphorylating or nonphosphorylating states has been evaluated. Mitochondrial respiration ...

Manfridi, Alfredo, Dario Brambilla, and Mauro Mancia. Stimulation of NMDA and AMPA receptors in the rat nucleus basalis of Meynert affects sleep. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1488–R1492, 1999.—The nucleus basalis of Meynert (NBM), a heterogeneous area in the basal forebrain involved in the modulation of sleep and wakefulness, is rich in glutamate receptors, a...

Prinz, Christian, Robert Zanner, Markus Gerhard, Sabine Mahr, Nina Neumayer, Barbara Höhne-Zell, and Manfred Gratzl. The mechanism of histamine secretion from gastric enterochromaffin-like cells. Am. J. Physiol. 277 (Cell Physiol. 46): C845–C855, 1999.— Enterochromaffin-like (ECL) cells play a pivotal role in the peripheral regulation of gastric acid secretion as they respond to the functionall...