نتایج جستجو برای: ماتریس mds

تعداد نتایج: 16566  

2016
A J I S Rathnayake H W W Goonasekera V H W Dissanayake

Bone marrow (BM) mesenchymal stem/stromal cells (MSCs) are vital in hematopoiesis. Whether BM-MSCs alter their characteristics in Myelodysplastic Syndromes (MDS) is still controversial. We characterized MSCs of de novo MDS patients in Sri Lanka who have not been reported previously in the literature. We also analyzed MSCs derived from different MDS subtypes. MSCs were culture-expanded, characte...

2009
Stanislav G. Kozmin Yuliya Sedletska Anne Reynaud-Angelin Didier Gasparutto Evelyne Sage

It has been stipulated that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. Using a variety of model multiply damaged sites (MDS), we investigated parameters that govern the formation of DSB during the processing of MDS. Duplexes carrying MDS were inserted into replicative or integrative vector...

2017
Peter Valent Attilio Orazi David P. Steensma Benjamin L. Ebert Detlef Haase Luca Malcovati Arjan A. van de Loosdrecht Torsten Haferlach Theresia M. Westers Denise A. Wells Aristoteles Giagounidis Michael Loken Alberto Orfao Michael Lübbert Arnold Ganser Wolf-Karsten Hofmann Kiyoyuki Ogata Julie Schanz Marie C. Béné Gregor Hoermann Wolfgang R. Sperr Karl Sotlar Peter Bettelheim Reinhard Stauder Michael Pfeilstöcker Hans-Peter Horny Ulrich Germing Peter Greenberg John M. Bennett

Myelodysplastic syndromes (MDS) comprise a heterogeneous group of myeloid neoplasms characterized by peripheral cytopenia, dysplasia, and a variable clinical course with about 30% risk to transform to secondary acute myeloid leukemia (AML). In the past 15 years, diagnostic evaluations, prognostication, and treatment of MDS have improved substantially. However, with the discovery of molecular ma...

Journal: :Blood 2006
Tony A Navas Mani Mohindru Myka Estes Jing Ying Ma Lubomir Sokol Perry Pahanish Simrit Parmar Edwin Haghnazari Li Zhou Robert Collins Irene Kerr Aaron N Nguyen Yin Xu Leonidas C Platanias Alan A List Linda S Higgins Amit Verma

The myelodysplastic syndromes (MDSs) are collections of heterogeneous hematologic diseases characterized by refractory cytopenias as a result of ineffective hematopoiesis. Development of effective treatments has been impeded by limited insights into any unifying pathogenic pathways. We provide evidence that the p38 MAP kinase is constitutively activated or phosphorylated in MDS bone marrows. Su...

Journal: :Expert Syst. Appl. 2010
Byoungsoo Kim

Due to the rapid growth of mobile data service (MDS), research into MDS continuance has recently emerged as an important issue in information systems (IS) and marketing literature. This study develops an integrated model designed to predict a user’s continuance behavior toward MDS based on the expectation–confirmation model (ECM) and the theory of planned behavior (TPB). Empirical data collecte...

2015
Anwarul Islam

Lenalidomide is an immunomodulatory drug which is used to treat patients with MDS with deletion 5q chromosomal abnormality. In 2008, WHO introduced a new disease entity called MDS/MPN. No specific treatment for MDS/MPN subtype has yet been identified. We report a patient with MDS/MPN who responded well to lenalidomide therapy.

H. Ghassemi H. Nowruzi

In the current study, five different atomistic water models (AWMs) are implemented, In order to investigate the impact of AWMs treatment on the water velocity profile and density number. For this purpose, Molecular dynamics simulation (MDS) of Poiseuille flow in a nano-channel is conducted. Considered AWMs are SPC/E, TIP3P, TIP4P, TIP4PFQ and TIP5P. To assessment of the ability of each model in...

Journal: :American journal of clinical pathology 2009
Kathryn Foucar

Myelodysplastic/myeloproliferative neoplasms (MDS/MPNs) are rare de novo myeloid neoplasms that exhibit hybrid dysplastic and proliferative features at presentation. This SHP/EAHP Workshop session was uniquely problematic owing to the overlap between MDS/MPNs and both chronic myeloproliferative neoplasms and myelodysplasia. The borderline between MDS/MPNs and overt acute myeloid leukemias was a...

2016
Ting Li Jian Bai Yao Sun Dingkang Wang Dongdai Lin

Maximal Distance Separable (MDS) matrices are important components for block ciphers. In this paper, we present an algorithm for searching 4×4 MDS matrices over GL(4,F2). By this algorithm, we find that all the lightest MDS matrices have only 10 XOR counts. Besides, all these lightest MDS matrices can be classified to 3 types, and some necessary and sufficient conditions are presented for them ...

2012
Cláudio César Monteiro de Castro Carlos Bellini Gondim Gomes Manoel Ricardo Alves Martins Juliana Cordeiro de Sousa Silvia MM Magalhaes Ronald F Pinheiro

Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder of elderly people. Cardiac dysfunction is a marker of grim prognosis in MDS. We evaluated cardiac dysfunction of MDS patients with or without transfusion dependency by tissue doppler echocardiography. We found the average values of ventricular end-systolic and end-diastolic volumes in transfusion dependency MDS group hi...

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