Président du jury : François JULIEN Directeur de Recherches(HDR), IEF – Univ. Paris Sud Rapporteurs : Olivier GAUTHIER-LAFAYE Chargé de Recherches(HDR), LAASUniv. Paul Sabatier Dominique COQUILLAT Directeur de Recherches(HDR), L2C –Univ. Montpellier 2 Examinateurs : Robson FERREIRA Directeur de Recherches(HDR), LPA – ENS de Paris Bloch oscillations and Wannier Stark Ladder study in Semiconducto...

Free flow electrophoresis (FFE) is a fractionation method, based on isoelectric focusing (IEF). We validate the reproducibility of the method and show that it can be applied by biobanks in order to fractionate fluid biospecimens efficiently and reproducibly and to facilitate downstream proteomic applications. We also propose a simple method allowing researchers to assess the reproducibility of ...

This follow-up paper completes the author's investigations to explore the in-solution structural preferences and relative free energies of all OH-substituted oxazole, thiazole, isoxazole, and isothiazole systems. The polarizable continuum dielectric solvent method calculations in the integral-equation formalism (IEF-PCM) were performed at the DFT/B97D/aug-cc-pv(q+(d))z level for the stable neut...

Using isoelectric focusing (IEF) and radial immunodiffusion (RID) techniques, serum samples from 100 normal healthy adults and 21 patients with pulmonary emphysema were analysed to identify various alpha 1 antitrypsin phenotypes and the serum concentrations. Ten percent of the patients had low serum values. The normal or most common genetic form, MM, is the predominant phenotype in both control...

We developed a simple and highly-sensitive enzyme activity assay method based on reagent release capillary – isoelectric focusing (RRC-IEF), that can be applied for the development of multi analyte sensing device allowing simple and highly sensitive multi assay of both proteins and enzyme activities.