background & aim : systemic lupus erythematosus (sle) is an autoimmune disease that affects primarily women, commonly in their reproductive years. clinicians have to face the many problems of pregnancy in patients with sle including the influence of sle on fetal outcome and that of pregnancy on sle. this study was performed to study maternal and fetal outcomes in women with sle. material and me...

introduction systemic lupus erythematous (sle) is among rheumatic diseases of unknown etiology. fever of unknown origin (fuo) has been rarely reported to be the presenting sign of sle. presence of four or more sle criteria is diagnostic for the disease. however, presentations may occur serially which make it much more difficult to diagnose an already questioned fuo. case presentation our case o...

In any description of leg ulcers in systemic lupus erythematosus (SLE), pyoderma gangrenosum (PG) earns a mention at least for its being quite rare in such patients. The causative role of aPL (antiphospholipid antibody) in dermatological manifestations of SLE is undermined by the occurrence of PG in aPL negative SLE patients. To the best of our knowledge, there are only two reports of PG in aPL...

introduction: systemic lupus erythematosus (sle) is an autoimmune disease affect nearly every organ system. pulmonary involvement, which is a common manifestation of sle, can remain undiagnosed if asymptomatic. this study aimed to evaluate the efficiency of spirometric findings in early detection of silent pulmonary involvement and examine its correlation with the six minute walk test in sle pa...

isolated hematuria and its association with proteinuria, and urinary cast and systemic lupus erythematosus (sle) disease activity, and decision for renal biopsy is a dilemma for physician in sle patients. the aim of this study was to investigate 1. whether isolated hematuria is associated with active sle, 2. to determine duration between hematuria and proteinuria and urinary cast, and 3. to det...

background: infection is now the most common cause of morbidity in systemic lupus erythematosus (sle). there is lack of information regarding the specific antibody forma-tion in response to vaccines in young sle patients. objective: to determine the efficacy of anti-tetanus antibody response in young patients with sle. methods: forty sle pa-tients with mean age of 14.1 years (range: 7-21) and 6...

Systemic lupus erythematous (SLE) is an autoimmune process in which cutaneous lesions occur in majority of patients. This study was conducted to determine the pattern and prevalence of such lesions in SLE in Iranian children infected with SLE. Forty-eight patients, age between 3-16 yrs and male to female ratio of 7/1 were examined for the presence of cutaneous manifestations of SLE. The most co...

Background: Infection is now the most common cause of morbidity in Systemic Lupus Erythematosus (SLE). There is lack of information regarding the specific antibody forma-tion in response to vaccines in young SLE patients. Objective: To determine the efficacy of anti-tetanus antibody response in young patients with SLE. Methods: Forty SLE pa-tients with mean age of 14.1 years (range: 7-21) and 6...

Background: Systemic Lupus Eyrythematosus (SLE) is an autoimmune disease charac-terized by antibodies to nuclear antigens, particularly anti-dsDNA. Imbalance between production and destruction of immune cells causes cytopenia. Sex hormones have im-munomodulatory effects; estrogen increases the production of autoantibodies in SLE prone NZB/NZW mice. Objective: To investigate the relationship bet...