Patients with chronic lymphocytic leukaemia (CLL) have an increased risk of new malignancies. However, limited data been published about the impact CLL treatment on this risk. Here we followed a Danish population-based cohort patients for risks in registry (2008–2017) were included. Up to 50 CLL-free matched comparators identified. First-line was categorized into four groups; bendamustine, chlo...

We recently reported that chronic lymphocytic leukemia (CLL) subgroups with distinct clonotypic BCRs present discrete patterns of TLR expression, function, and/or tolerance. In this study, to explore whether specific types of BCR/TLR collaboration exist in CLL, we studied the effect of single versus concomitant BCR and/or TLR stimulation on CLL cells from mutated (M-CLL) and unmutated CLL (U-CL...

Ecthyma Gangrenosum is a severe skin disease commonly associated with Pseudomonas aeruginosa septicemia, there an increased risk of infection in patients malignancy undergoing chemotherapy notably Chronic lymphocytic leukemia (CLL). We present case report CLL patient infested by P. aeruginosa.

Chronic lymphocytic leukemia (CLL) is one of the most common lymphoproliferative diseases in European population with an increase incidence elderly and senile age. However, it among that a decrease glomerular filtration rate (GFR) concomitant chronic kidney disease (CKD) are associated severity long-term prognosis.
 The aim study was to analyze CKD prognostic value patients CLL.
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Background: Chronic lupoid leishmaniasis (CLL) is a chronicform of cutaneous leishmaniasis that is usually resistant to antileishmania agents and leishmania is not seen in the histologicsections. We used polymerase chain reaction (PCR) to detectleishmania DNA in CLL specimens.Method: This descriptive cross sectional study was done on20 paraffin embedded specimens of CLL cases referred to theder...

B-cell chronic lymphocytic leukemia (CLL), the most common leukemia in the Western world. CLL occurs in two forms, aggressive and indolent. Aggressive CLL is characterized by high ZAP-70 expression and unmutated IgH V(H); indolent CLL shows low ZAP-70 expression and mutated IgH V(H). We recently found that miR-29 is up-regulated in indolent human B-CLL, compared to aggressive B-CLL and normal C...