نتایج جستجو برای: قطعنامه 181 تقسیم

تعداد نتایج: 52993  

Journal: :Journal of clinical and diagnostic research : JCDR 2013
M Shanthi Uma Sekar Arunagiri K Hemant Goverdhandas Bramhne

BACKGROUND Detection of carbapenem hydrolyzing class D beta lactamase OXA-181, (a variant of OXA-48) in Enterobacteriaceae, is important, to institute appropriate therapy and to initiate preventive measures. This study was done to determine the presence of OXA 48 and its derivative OXA-181 in Enterobacteriaceae of pathogenic significance. MATERIAL AND METHODS One hundred and eleven non-repeti...

2018
Honghai Hong Yingmin Zeng Wenxuan Jian Lei Li Liying Lin Yousheng Mo Meiling Liu Shuhuan Fang Yong Xia

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability. Anti-inflammatory drugs and disease-modifying anti-rheumatic drugs (DMARDs) may improve RA process. However, in most patients the treatment effect is still not satisfactory. Cyclin-dependent kinase 7 (CDK7) plays a well-e...

Journal: :Dementia and geriatric cognitive disorders 2010
Igor Yakushev Peter Bartenstein Thomas Siessmeier Christoph Hiemke Armin Scheurich Johannes Lotz Andreas Fellgiebel Matthias J Müller

AIMS In this study, we aimed to compare cerebrospinal fluid (CSF) levels of total tau (t-tau), phosphorylated tau (p-tau(181)) and positron emission tomography with (18)F-fluorodeoxyglucose (FDG-PET) in the differential diagnosis of Alzheimer's disease (AD) under clinical conditions. METHOD In a cross-sectional, blinded, single-center study, we examined a sample of 75 unselected memory clinic...

2016
Aleksandra Butrym Justyna Rybka Dagmara Baczyńska Rafał Poręba Grzegorz Mazur Kazimierz Kuliczkowski

MicroRNAs (miRs) are small non-coding RNAs that play important roles in cell differentiation and survival. Abnormal expression of miRs has been demonstrated in numerous types of cancer, including acute myeloid leukaemia (AML). The aim of the present study was to evaluate miR-181 expression at diagnosis and following the completion of chemotherapy in AML patients, with regard to clinical respons...

2016
Hongbo Chen Yanhong Duo Bo Hu Zhiwei Wang Fang Zhang Hsiangi Tsai Jianping Zhang Lanzhen Zhou Lijun Wang Xinyu Wang Laiqiang Huang

PICT-1 was originally identified as a tumor suppressor. Here, we found that PICT-1 overexpression triggered pro-death autophagy without nucleolar disruption or p53 accumulation in U251 and MCF7 cells. Truncated PICT-1 fragments 181-346 and 1-346, which partly or totally lack nucleolar localization, showed weaker autophagy-inducing effects than full-length PICT-1 and a well-defined nucleolar mut...

2016
Chwan Hong Foo Christina L Rootes Karla Cowley Glenn A Marsh Cathryn M Gould Celine Deffrasnes Christopher J Cowled Reuben Klein Sarah J Riddell Deborah Middleton Kaylene J Simpson Lin-Fa Wang Andrew G D Bean Cameron R Stewart

Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are bat-borne viruses that cause fatal disease in humans and a range of other mammalian species. Gaining a deeper understanding of host pathways exploited by henipaviruses for infection may identify targets for new anti-viral therapies. Here we have performed genome-wide high-throughput agonist and antagonist screens at biosaf...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Elsa C Y Yan Manija A Kazmi Ziad Ganim Jian-Min Hou Douhai Pan Belinda S W Chang Thomas P Sakmar Richard A Mathies

The biological function of Glu-181 in the photoactivation process of rhodopsin is explored through spectroscopic studies of site-specific mutants. Preresonance Raman vibrational spectra of the unphotolyzed E181Q mutant are nearly identical to spectra of the native pigment, supporting the view that Glu-181 is uncharged (protonated) in the dark state. The pH dependence of the absorption of the me...

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