Treatment of anhydrous FeX2 (X = Cl, Br) with 1 equiv. of the asymmetric chiral PNP pincer ligands PNP-R,TAD (R = iPr, tBu) with an R,R-TADDOL (TAD) moiety afforded complexes of the general formula [Fe(PNP)X2]. In the solid state these complexes adopt a tetrahedral geometry with the PNP ligand coordinated in κ(2)P,N-fashion, as shown by X-ray crystallography and Mössbauer spectroscopy. Magnetiz...

Alkynes and olefins insert into [(IPr)CuH] 2 (IPr = N,N-bis-(2,6diisopropylphenyl)-1,3-imidazol-2-ylidene) to give copper vinyl and copper alkyl complexes. These copper complexes insert CO2 into the Cu-C bond to form copper acrylate and copper carboxylate complexes. Acrylic and carboxylic acids can be isolated

New compound Zn[(S,S)-iPr-pybox](Et)(2) (1) was fully characterized, including by X-ray diffraction structural studies. Its grafting onto partially dehydroxylated silica affords material 2, which bears well-defined chiral ([triple bond]SiO)Zn[(S,S)-iPr-pybox](Et) sites. Hybrid material 2 displays significantly better catalytic performances than 1 in enantioselective silylcyanation, thus demonst...

Inventors can commercialize innovative products by themselves and simultaneously license the technology to other firms. The licensee may cannibalize sales of the licensor, but this can be compensated by gains from royalties. We show in this paper how licenses can be used strategically to speed up the new product diffusion process in two instances of markets: (i) a market with strong Intellectua...

AIM OF STUDY Intrathoracic pressure regulation (IPR) has been used to treat hypotension and states of hypoperfusion by providing positive pressure ventilation during inspiration followed by augmentation of negative intrathoracic pressure during expiration. This therapy augments cardiac output and lowers intracranial pressure, thereby providing greater circulation to the heart and brain. The eff...

A three-dimensional model of the variable domain of the atrazine-specific Fab fragment K411B was constructed by molecular modeling using known structures of highly homologous immunoglobulins as templates. Molecular dynamic simulations and cross-reactivity data were used to predict residues responsible for the binding of the hapten 4-chloro-6-(isopropylamino)-1,3,5-triazine-2-(6-aminohexanecarbo...

Rhodium-alkene complexes of the pincer ligand ?3-C5H3N-2,6-(OPiPr2)2 (PONOP-iPr) have been prepared and structurally characterized: [Rh(PONOP-iPr)(?2-alkene)][BArF4] [alkene = cyclooctadiene (COD), norbornadiene (NBD), ethene; ArF 3,5-(CF3)2C6H3]. Only one these, alkene COD, undergoes a reaction with H2 (1 bar), to form [Rh(PONOP-iPr)(?2-COE)][BArF4] (COE cyclooctene), while others show no sign...

Unusual N-N coupling of aryl azides to yield azoarenes is demonstrated by the Ru(I) metalloradical, [SiP(iPr)(3)]Ru(N(2)) (4) ([SiP(iPr)(3)] = (2-iPr(2)PC(6)H(4))(3)Si(-)). The yield of the azoarene is dependent on the substituent on the aryl azide, and the reaction is catalytic for p-methoxy and p-ethoxy phenyl azides, while no azoarene is observed for p-trifluoromethylphenyl azide. Studies ai...