Simple synthetic routes to regioselectively deuterated tris[2-(dimethylamino)ethyl]amine (Me6TREN) variants are described. Imine formation with formaldehyde-d2 from tris(2-aminoethyl)amine (TREN) and subsequent reductions NaBD4 afforded N[CH2CH2N(CD3)2]3 or d18-Me6TREN in 79 % yield. A trisubstitution protocol 2-bromo-N,N-dimethylacetamide ammonium carbonate reduction of the N(CH2CONMe2)3 inter...

All the possible three-family ${\cal N}=1$ supersymmetric Pati-Salam models constructed with intersecting D6-branes from Type IIA orientifolds on $T^6/(\mathbb{Z}_2\times \mathbb{Z}_2)$ are recently presented in arXiv: 2112.09632. Taking largest wrapping number $5$ and approximate gauge coupling unification at GUT scale as examples, we show string can be realized through two-loop renormalizatio...

The substituted benzimidazoles omeprazole, lansoprazole, rabeprazole, and pantoprazole were found to have in vitro activity against three different isolates of Plasmodium falciparum: D6 (which is chloroquine and pyrimethamine sensitive), W2 (chloroquine and pyrimethamine resistant), and TM91C235 (multidrug resistant). Lansoprazole and rabeprazole were the most effective against all three isolat...

We construct new supersymmetric SU (5) Grand Unified Models based on Z 4 × Z 2 orientifolds with intersecting D6-branes. Unlike constructions based on Z 2 × Z 2 orientifolds, the orbifold images of the three-cycles wrapped by D6-branes correspond to new configurations and thus allow for models in which, in addition to the chiral sector in 10 and ¯ 5 representations of SU (5), only, there can be...