objective:platycladus orientalis or thuja orientalis is a native plant of iran different parts of which are used in the treatment of various diseases such as: gout, rheumatoid arthritis, common cold, cough, bronchitis, asthma, high blood pressure and hormonal disorders like hirsutism and baldness. also, various organs of this species have been used as appetizer. the purpose of this study was to...

a rapid and sensitive hplc method has been developed for the quantification of mirtazapine (mrz), a noradrenergic and specific serotonergic inhibitor antidepressant (nassa) and its two major metabolites n-desmethylmirtazapine (ndm) and 8-hydroxymirtazapine (8-ohm) in human plasma. the separation was achieved using chromolith c18 column and a mobile phase of acetonitrile: phosphate buffer (ph=3,...

impurities of drug substances may produce some side effects in patient. diclofenac na is a member of non-steroidal anti inflammatory drugs (nsaids) family, which is routinely used by patients for the treatment of rheumatoid arthritis and various pains. to develop a method for the determination of synthetic precursors which could be remained as impurities in raw drug materials, na diclofenac pow...

eperisone hydrochloride is a skeletal muscle relaxant and paracetamol is cyclooxygenase inhibitor. these drugs in combination are used as antispasmodics. a simple, specific, precise and accurate method was developed, namely reverse phase high performance liquid chromatography for simultaneous estimation of eperisone hydrochloride and paracetamol in tablet dosage form. in rp-hplc method separati...

biogenic amines (ba) are nitrogenous compounds that possess biological activity. the source of production is the microbial decarboxylation of amino acids. this compounds are found in various types of cheese. the aim of this work was to evaluate the ba content of some traditional cheeses in west azerbaijan province iran. for this purpose, 70 samples of koopeh, 10 samples of lighvan and 5 samples...

use of raw milk and dairy products containing aflatoxin m1 (afm1) has led to concern inconsumers. the present study determined the afm1 in raw cow's milk in qazvinprovince. in this research, 170 raw cow's milk were collected from dairy farm, dairyfactories, milk collection centers, and milk supply centers in qazvin province during coldseasons in 2013, and all samples were examined for afm1. the...

oligosaccharide prepared from Pl.-B was eluted as a single peak on both reversed-phase {RP-) HPLC and size-fractionation (SF-) HPLC, and its strueture was estimated to be Manoct-qManal -. 3)(Xylfi1-.2) Manfi1-4GlcNAcfi1-4(Fuc=1-3)GlcNAc by a combination of component analysis, successive exogl)'cosidase digestions, IS-MS anal)'sis, and 500MHz 'H-NMR, Two tryptic gl)'copeptides were isolated from...

Filtration is a common method of sample preparation in dissolution testing, prior to HPLC injection. The purpose of sample filtration is to remove non-dissolved solids prior to HPLC injection. Non-dissolved solids interfere with the resulting chromatography by continuing to dissolve throughout the period of the analysis and also by plugging the HPLC column. It has already been shown that sample...