Electroconvulsive therapy (ECT) is the most effective treatment for severe major depressive episodes (MDE). Nonetheless, firmly established associations between ECT outcomes and biological variables are currently lacking. Polygenic risk scores (PRSs) carry clinical potential but with response in psychiatry seldom reported. Here, we examined whether PRSs disorder, schizophrenia, cross-disorder, ...

Introduction Major depressive disorder is one of the most common and disabling mental disorders. More than 30% individuals do not achieve remission after several trials antidepressants treatment-resistant depression (TRD) associated with premature mortality. Electroconvulsive therapy (ECT) considered gold-standard for TRD treatment,unfortunately it´s underused due to health care barriers associ...

Abstract Autobiographical memory loss is a common complaint of patients treated with electroconvulsive therapy (ECT). However, reliable measurement autobiographical after ECT still subject debate. In the 1990s, Colombia University Memory Interview (CUAMI) was developed specifically to monitor changes in during course ECT. this instrument has been criticized due lack psychometric data. talk, we ...