Hypericum perforatum (St John's wort) is a well known medicinal plant used in many pharmaceutical formulations and its main active compound is hypericin. The purpose of our study was to examine the plasma level of hypericin upon long term mice treatment with Hyperici herba extract. A reversible hyperthermia was recorded upon 2 hours of the extract administration, both in males and females. Hype...

Herb-induced liver injury (HILI) has recently attracted attention due to increasing reports of hepatotoxicity associated with use of phytotherapeutics. Here, we present data on HILI from the Berlin Case-Control Surveillance Study. The study was initiated in 2000 to investigate the serious toxicity of drugs including herbal medicines. Potential cases of liver injury were ascertained in more than...

Homeopathic remedies are produced by potentising, that is, the serial logarithmic dilution and succussion of a mother tincture. Techniques like ultraviolet spectroscopy, nuclear magnetic resonance, calorimetry, or thermoluminescence have been used to investigate their physical properties. In this study, homeopathic centesimal (c) potencies (6c to 30c) of copper sulfate, Hypericum perforatum, an...

Hypericum perforatum (St. John's wort) is well-established for its antidepressant activity throughout the world and also various other species within this genus are used in different folk medicines. Hyperforin of St. John's wort inhibited growth of cancer cell lines and the use of hypericin (another compound of H. perforatum) in cancer photodynamic therapy is proposed. Therefore, we investigate...

Mary Ellen Avery Treasurer Francisco J. Ayala Richard S. Nicholson Robert A. Frosch Executive Officer John Abelson Frederick W. Alt Don L. Anderson Stephen J. Benkovic David E. Bloom Floyd E. Bloom Henry R. Bourne James J. Bull Kathryn Calame C. Thomas Caskey Dennis W. Choi John M. Coffin Bruce F. Eldridge Paul T. Englund Richard G. Fairbanks Douglas T. Fearon Harry A. Fozzard Victor R. Fuchs T...

Kai-Ming G. Fu,1,2 Taylor A. Johnston,1,2 Ankoor S. Shah,1,2 Lori Arnold,3 John Smiley,2 Troy A. Hackett,4 Preston E. Garraghty,3 and Charles E. Schroeder1,2 1Albert Einstein College of Medicine, Bronx, New York 10461, 2Nathan Kline Institute, Orangeburg, New York 10962, 3Department of Psychology, Program in Neural Science, Indiana University, Bloomington, Indiana 47405, and 4Vanderbilt Univers...

D. A fourth claim is that the St Lucia House and associated publications, exemplify an appropriate model for future research by design within the field of architecture. ........................................................................................................................................ A. The component arguments for (1) Environmental, (2) Urban Design, (3) Social, (4) Spatial...

BACKGROUND Recent investigations suggest an anti-inflammatory and antibacterial effect of hyperforin, which is a major constituent of Hypericum perforatum L. (Saint John's wort). OBJECTIVE In the present half-side comparison study we assessed the efficacy of a cream containing Hypericum: extract standardised to 1.5% hyperforin (verum) in comparison to the corresponding vehicle (placebo) for t...

with the tremendous expansion in the use of herbal medicine worldwide, safety and efficacy as well as quality control of herbal medicine have become important concerns for both health authority and public. in this paper, the analysis of two st. john's wort (hypericum perforatum) products and four liquorice (glycyrrhiza glabra) products by spectrophotometric and hplc methods, is explained. moreo...