The aim of our study was to test the immunosuppressive effect of gemcitabine in monotherapy following heterotopic SBT in the rat. The BN and LEW rats were used as donors and recipients, respectively. Recipients were divided into 4 groups--group A without immunosuppression, group B treated with a therapeutic dose of tacrolimus, groups C and D treated with various doses of gemcitabine (100 and 15...

Patient safety is an issue of imminent concern in the high-risk field of medicine, and systematic changes that alter the way medical professionals approach patient care are needed. Simulation-based training (SBT) is an exemplary solution for addressing the dynamic medical environment of today. Grounded in methodologies developed by the aviation industry, SBT exceeds traditional didactic and app...

BACKGROUND Embryologists currently face a challenge when counselling patients regarding the stage and the number of embryos to transfer when no top-quality embryos (TQE) are available. METHODS The aim of this study was to evaluate the efficacy of single blastocyst transfer (SBT) in comparison with the transfer of two cleavage-stage embryos in women under 36 years old. A total of 450 women under...

Background: Correlation between prediction tools of disability and traditional physical performance tests in ascertaining risks remains unexplored. Objectives: The present study aimed to assess the convergent validity STarT back tool (SBT) for predicting risk using spinal range motion (ROM). Methods: Thirty patients with low-back pain (LBP) volunteered this study. We used SBT Dual inclinometers...

OBJECTIVE To examine the clinical pregnancy rate (CPR) and multiple pregnancy rate (MPR) in a large in vitro fertilisation (IVF) programme before and after the introduction of single blastocyst transfer (SBT) strategy in a selected group of women. DESIGN A 3-year pre- and postintervention study. SETTING A tertiary reproductive medicine and assisted conception unit in a London teaching hospi...

The objective of this study was to evaluate the effects of lung perfusion on the slopes of phases II (S(II)) and III (S(III)) of a single-breath test of CO(2) (SBT-CO(2)). Fourteen patients submitted to cardiac surgery were studied during weaning from cardiopulmonary bypass (CPB). Pump flow was decreased in 20% steps, from 100% (total CPB = 2.5 l.min(-1).m(-2)) to 0%. This maneuver resulted in ...

Mucositis is a common and debilitating side effect of chemotherapy that manifests due to the inability of chemotherapy agents to discriminate between normal and neoplastic cells. This results in ulcerating lesions lining the gastrointestinal tract. Moreover, the development of efficacious treatments for small intestinal mucositis has been hindered as the pathobiology of mucositis is still not f...

introduction  mechanical ventilation may be lifesaving intervention,it can be associated with complications,thus,successful weaning is constitutive.one of the factors which is  important in successful weaning is  method of weaning. it is shown that  weaning is conducted successfully by using spontaneous breathing trial (sbt) through t-piece and pressure support (ps) ventilation.but few studies ...

Background: Symptom-to-balloon time (SBT) and door-to-balloon (DBT) are both considered important metrics in patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment–elevation myocardial infarction (STEMI). We sought to assess the relationship of SBT DBT with infarct size microvascular obstruction (MVO) after pPCI. Methods: Individual patient data 3115 pPCI 10 random...