نتایج جستجو برای: ضریب تغییرات cov

تعداد نتایج: 158079  

Journal: :Emerging infectious diseases 2016
Basem M Alraddadi John T Watson Abdulatif Almarashi Glen R Abedi Amal Turkistani Musallam Sadran Abeer Housa Mohammad A Almazroa Naif Alraihan Ayman Banjar Eman Albalawi Hanan Alhindi Abdul Jamil Choudhry Jonathan G Meiman Magdalena Paczkowski Aaron Curns Anthony Mounts Daniel R Feikin Nina Marano David L Swerdlow Susan I Gerber Rana Hajjeh Tariq A Madani

Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March-November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before il...

2017
Soo Young Jeong Se In Sung Ji Hee Sung So Yoon Ahn Eun Suk Kang Yun Sil Chang Won Soon Park Jong Hwa Kim

Middle East respiratory syndrome (MERS) is a lethal respiratory disease - caused by MERS-coronavirus (MERS-CoV) which was first identified in 2012. Especially, pregnant women can be expected as highly vulnerable candidates for this viral infection. In May 2015, this virus was spread in Korea and a pregnant woman was confirmed with positive result of MERS-CoV polymerase chain reaction (PCR). Her...

Journal: :Cell host & microbe 2017
Lucía Morales Juan Carlos Oliveros Raúl Fernandez-Delgado Benjamin Robert tenOever Luis Enjuanes Isabel Sola

Severe acute respiratory syndrome coronavirus (SARS-CoV) causes lethal disease in humans, which is characterized by exacerbated inflammatory response and extensive lung pathology. To address the relevance of small non-coding RNAs in SARS-CoV pathology, we deep sequenced RNAs from the lungs of infected mice and discovered three 18-22 nt small viral RNAs (svRNAs). The three svRNAs were derived fr...

Journal: :Journal of medicinal chemistry 2006
Keng-Chang Tsai Shih-Yuan Chen Po-Huang Liang I-Lin Lu Neeraj Mahindroo Hsing-Pang Hsieh Yu-Sheng Chao Lincoln Liu Donald Liu Wei Lien Thy-Hou Lin Su-Ying Wu

The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) 3C-like protease (3CL(pro) or M(pro)) is an attractive target for the development of anti-SARS drugs because of its crucial role in the viral life cycle. In this study, a compound database was screened by the structure-based virtual screening approach to identify initial hits as inhibitors of SARS-CoV 3CL(pro). Out of the 5...

2016
Farida Ismail Al Hosani Kimberly Pringle Mariam Al Mulla Lindsay Kim Huong Pham Negar N. Alami Ahmed Khudhair Aron J. Hall Bashir Aden Feda El Saleh Wafa Al Dhaheri Zyad Al Bandar Sudhir Bunga Kheir Abou Elkheir Ying Tao Jennifer C. Hunter Duc Nguyen Andrew Turner Krishna Pradeep Jurgen Sasse Stefan Weber Suxiang Tong Brett L. Whitaker Lia M. Haynes Aaron Curns Susan I. Gerber

In January 2013, several months after Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia, Abu Dhabi, United Arab Emirates, began surveillance for MERS-CoV. We analyzed medical chart and laboratory data collected by the Health Authority-Abu Dhabi during January 2013-May 2014. Using real-time reverse transcription PCR, we tested respiratory tract samples ...

2007
Marcel A. Müller Janusz T. Paweska Patricia A. Leman Christian Drosten Klaus Grywna Alan Kemp Leo Braack Karen Sonnenberg Matthias Niedrig Robert Swanepoel

Asian bats have been identified as potential reservoir hosts of coronaviruses associated with severe acute respiratory syndrome (SARS-CoV). We detected antibody reactive with SARS-CoV antigen in 47 (6.7%) of 705 bat serum specimens comprising 26 species collected in Africa; thus, African bats may harbor agents related to putative group 4 CoV.

2014
Daniel K.W. Chu Leo L.M. Poon Mokhtar M. Gomaa Mahmoud M. Shehata Ranawaka A.P.M. Perera Dina Abu Zeid Amira S. El Rifay Lewis Y. Siu Yi Guan Richard J. Webby Mohamed A. Ali Malik Peiris Ghazi Kayali

We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-CoV infections have not yet been detected.

2015
Mahtab Shahkarami Cynthia Yen Carol Glaser Dongxiang Xia James Watt Debra A. Wadford

Since Middle East respiratory syndrome coronavirus (MERS-CoV) first emerged, the California Department of Public Health has coordinated efforts to identify possible cases in travelers to California, USA, from affected areas. During 2013-2014, the department investigated 54 travelers for MERS-CoV; none tested positive, but 32 (62%) of 52 travelers with suspected MERS-CoV had other respiratory vi...

ژورنال: :پژوهنده 0
دکتر مسعود مردانی masoud mardani infectious diseases and tropical medicine research center, shahid beheshti university of medical science, tehran, iran; phone: +98 21 22439968مرکز تحقیقات بیماری های عفونی و گرمسیری، دانشگاه علوم پزشکی شهید بهشتی، تلفن: 22439968 (021)؛ دکتر زهرا ابطحیان zahra abtahian کسری مردانی kasra mardani

(mers) یک بیماری ویروسی تنفسی است که اولین بار در سپتامبر 2012 در جده عربستان سعودی گزارش شد. عامل بیماری، یک ویروس جدید از گروه بتاکوروناویروسها است که تا این مرحله منشاء آن نامشخص است؛ ولی مطالعات ژنتیکی حاکی از آن است که کوروناویروسهای خفاش بیشترین نزدیکی را به این ویروس دارند. به طور کلی، mers-cov به نظر یک ویروس حیوانی است که به صورت اسپورادیک و با انتقال محدود، منجر به عفونت در انسان می ش...

Journal: :Current infectious disease reports 2013
Poh Lian Lim Tau Hong Lee Emily K Rowe

Middle East Respiratory Syndrome coronavirus (MERS CoV) came to attention as an emerging pathogen causing severe respiratory illness in patients from the Middle East in September 2012. As of 14 June 2013, 58 human cases of MERS CoV infection have been confirmed, including 33 deaths (case fatality rate of 57%). MERS CoV is a beta-coronavirus, in the same family as SARS-CoV, and shares a probable...

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