نتایج جستجو برای: شاخص تعادل رقابتی c5 c5icb
تعداد نتایج: 99351 فیلتر نتایج به سال:
A new 3D, spin-state-selective coherence transfer NMR experiment is described that yields accurate measurements for eight scalar or dipolar couplings within a spin system composed of a methylene adjacent to a methine group. Implementations of the experiment have been optimized for proteins and for nucleic acids. The experiments are demonstrated for Cbeta-Calpha moieties of the third IgG-binding...
The defect in Leiner's disease, which presents in early infancy with extensive dermatitis, diarrhoea, and failure to thrive, has been attributed to a defect of the fifth component of complement (C5). We report 2 brothers with extensive dermatitis and dysgammaglobulinaemia. Both died. The older showed symptoms of Leiner's disease: C5 tests were not performed. The younger had extensive dermatitis...
امروزه، صادرات مهمترین شاخص در توسعة جهانی شرکتها، همچنین کشورها محسوب میشود. توجه به بازارگرایی صادارت و مزیت رقابتی برای افزایش عملکرد صادرات اهمیت دارد. در مطالعة حاضر تأثیر بالقوة بازارگرایی صادرکنندگان و مزیت رقابتی بر عملکرد صادرات بررسی شده است. جامعة این تحقیق صادرکنندگان نمونة کشوری در سال 1390 بودند که هر ساله به مناسبت روز ملی صادرات از طریق وزارت صنعت، معدن و تجارت، و سازمان توسع...
تمرکز شدید و عدم تعادل منطقه ای نتایج سیاستهای رشد قطبی به شمار می آید که در نتیجه، تعدادی از مناطق نقش کلیدی گرفته و سایر مناطق به صورت حاشیه ای عمل می نمایند. اولین گام در برنامه ریزی منطقه ای برای ایجاد تعادل ، شناخت نابرابریهای نواحی مختلف و تعیین ساختار سلسله مراتبی می باشد . تحقیق حاضر بحث ساختار سلسه مراتب سکونتگاهی و تعیین الگوی فضایی بهینه را دنبال می کند و هدف آن بررسی شکافها و کمبو...
(1S,2S,3E,7E,11E)-3,7,11,15-cembratetraen-17,2-olide (LS-1), a marine cembrenolide diterpene, has anticancer activity against colon cancer cells such as HT-29, SNU-C5/5-FU (fluorouracil-resistant SNU-C5) and SNU-C5. However, the action mechanism of LS-1 on SNU-C5 human colon cancer cells has not been fully elucidated. In this study, we investigated whether the anticancer effect of LS-1could res...
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn.
Eculizumab is a humanized IgG2/4 chimeric anti-complement C5 antibody used to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) or atypical hemolytic uremic syndrome. The aim of this study was to evaluate whether or not the complement activity in newborns from pregnant women who receive eculizumab is impaired. A novel eculizumab-C5 complex (E-C5) specific assay was developed and rev...
C5-BPP is a highly efficient N-donor ligand for the separation of trivalent actinides, An(iii), from trivalent lanthanides, Ln(iii). The molecular origin of the selectivity of C5-BPP and many other N-donor ligands of the BTP-type is still not entirely understood. We present here the first NMR studies on C5-BPP Ln(iii) and An(iii) complexes. C5-BPP is synthesized with 10% 15N labeling and charac...
Membranoproliferative glomerulonephritis (MPGN) type II (dense deposit disease) is an inflammatory renal disease characterized by electron-dense deposits and complement C3 on the glomerular basement membrane. There is no effective therapy. We investigated the role of C5 activation in a model of MPGN that develops spontaneously in complement factor H-deficient mice (Cfh(-/-)). At 12 months there...
The aim of this study was to compare the antagonistic properties of Lactobacillus casei GG exerted in vitro against Salmonella typhimurium C5 in a cellular model, cultured enterocyte-like Caco-2 cells, to those exerted in vivo in an animal model, C3H/He/Oujco mice. Our results show that a 1-h contact between the invading strain C5 and either the culture or the supernatant of L. casei GG impeded...
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