نتایج جستجو برای: سیستم ترمیم mmr
تعداد نتایج: 81302 فیلتر نتایج به سال:
Among the techniques of video processing, video summarization is a promising approach to process the multimedia content. In this paper we present a novel summarization algorithm, Balanced Audio Video Maximal Marginal Relevance (Balanced AV-MMR or BAV-MMR), for multi-video summarization based on both audio and visual information. Balanced AVMMR exploits the balance between audio information and ...
Objective: Mismatch repair (MMR) deficiency can lead to genome instability and closely correlated with carcinogenesis of endometrial carcinoma and mainly caused by MMR gene germline mutation known as Lynch syndrome (LS) or epigenetic mechanisms of MLH1 promoter methylation. The main objective of the present study is to correlate the clinicopathological features in endometrial carcinoma from 92 ...
BACKGROUND India accounts for 19% of global maternal deaths, three-quarters of which come from nine states. In 2005, India launched a conditional cash transfer (CCT) programme, Janani Suraksha Yojana (JSY), to reduce maternal mortality ratio (MMR) through promotion of institutional births. JSY is the largest CCT in the world. In the nine states with relatively lower socioeconomic levels, JSY pr...
BACKGROUND The measles, mumps and rubella (MMR) vaccine has been the focus of considerable adverse publicity in recent years. AIM To describe recent trends in parental attitudes to, and coverage of, MMR vaccine. DESIGN OF STUDY Routine surveillance of vaccine coverage and cross-sectional surveys of parental attitudes. SETTING All health authorities in England (vaccine coverage) and 132 en...
OBJECTIVES To investigate whether measles, mumps, and rubella (MMR) vaccination is associated with bowel problems and developmental regression in children with autism, looking for evidence of a "new variant" form of autism. DESIGN Population study with case note review linked to independently recorded vaccine data. SETTING Five health districts in north east London. PARTICIPANTS 278 child...
Malaria a major parasitic infection globally particularly in tropical and sub-tropical regions of the world is responsible for about 198 million cases and estimated deaths due to this disease are about 0.6 million. The emergence of drug resistance in the malaria parasite is alarming and it is necessary to understand its underlying cause and molecular mechanisms. It has been established that dru...
403 Background: Colorectal cancer patients with deficient mismatch repair (dMMR) have significantly fewer recurrences and may respond less well to chemotherapy. Immunohistochemical (IHC) determination of MMR status is therefore recommended to identify patients in whom adjuvant therapy is not indicated, but little is known regarding the variability of assay results. We aimed to define MMR IHC as...
Colorectal cancers associated with Lynch syndrome are characterized by deficient DNA mismatch repair (MMR) function. Our aim was to evaluate the prevalence of microsatellite instability (MSI) and loss of MMR protein expression in Lynch syndrome-associated polyps. Sixty-two colorectal polyps--37 adenomatous polyps, 23 hyperplastic polyps, and 2 sessile serrated polyps (SSP)--from 34 subjects wit...
Sub-Saharan Africa has the highest ratio of maternal deaths in the world. Despite some progress, it is uncertain if Ghana (like other sub-Saharan countries) can reduce, by three-quarters, the maternal mortality ratio (MMR) by the year 2015 Therefore, the primary purpose of this study was to determine the predictors of MMR in Ghana. The study utilized data from the Demographic and Health Survey ...
BACKGROUND Cyclooxygenase 2 (COX-2) overexpression is a frequent but not universal event in colorectal cancer. It has been suggested that COX-2 protein expression is reduced in colorectal cancer with a defective mismatch repair (MMR) system, a phenomenon commonly associated with hereditary nonpolyposis colorectal cancer (HNPCC) but also present in up to 15% of sporadic tumors. AIM To assess C...
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