ACTIVATION PEPTIDE IS ESSENTIAL FOR AUTOACTIVATION CONTROL, BUT NOT FOR ENTEROPEPTIDASE RECOGNITION. Zsófia Nemoda and Miklós Sahin-Tóth From the Department of Molecular and Cell Biology, Boston University, Goldman School of Dental Medicine, Boston, MA, 02118 Running title: Trypsinogen activation peptide. Address correspondence to Miklós Sahin-Tóth, 715 Albany Street, Evans-433; Boston, MA 0211...

Lyme disease is sometimes part of the differential diagnosis for amyotrophic lateral sclerosis (ALS). Herein we report on 414 individuals with ALS at the Massachusetts General Hospital who underwent laboratory testing for Lyme disease. Twenty-four (5.8%) were seropositive, but only 4 (0.97%) had confirmed past immunoreactive infection. Two of these patients received ceftriaxone for 1 month with...

Vitamin D Repletion Reduces the Progression of Premalignant Squamous Lesions in the NTCU Lung Squamous Cell Carcinoma Mouse Model1 Sarah A. Mazzilli1, Pamela A. Hershberger2, Mary E. Reid3, Paul N. Bogner4, Kristopher Atwood5, Donald L. Trump6 and Candace S. Johnson2 Corresponding Author: Sarah A. Mazzilli, PhD Postdoctoral Fellow Boston University Division of Computational Biomedicine 72 East...

Brian D. Schmit, PhD 12 Marquette University 13 Department of Biomedical Engineering 14 P.O. Box 1881 15 Milwaukee, WI 53201-1881 16 17 Phone: (414) 288-6125 18 Fax: (414) 288-7938 19 20 Email: [email protected] 21 22 23 Running Title: Reflex Response to Active-Assist Elbow Movements Post-Stroke 24 25 26 27 28 29 30 31 Articles in PresS. J Neurophysiol (June 24, 2009). doi:10.1152/jn.9...

Running Title: Human HMG-CoA Lyase-Mg-Substrate/Inhibitor Structures To whom correspondence should be addressed: Jung-Ja P. Kim, Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226 Tel.: 414-955-8479 Fax: 414-456-6510, e-mail: [email protected]; Henry M. Miziorko, the Division of Molecular Biology and Biochemistry, University of Missouri-K...

http://dx.doi.org/10.1016/j.chb.2014.03.037 0747-5632/ 2014 Elsevier Ltd. All rights reserved. ⇑ Corresponding author. Address: Department of Communication, University of Wisconsin-Milwaukee, 2522 E. Hartford Ave, Milwaukee, WI 53201, USA. Tel.: +1 414 229 1753; fax: +1 414 229 4261. E-mail addresses: [email protected] (N. Park), [email protected] (H. Song), [email protected] (K.M. Lee). Namkee Pa...

The peptide nucleic acid (PNA)-directed PCR clamping technique was modified and applied to the detection of mitochondrial DNA mutations with low heteroplasmy. This method is extremely specific, eliminating false positives in the absence of mutant molecules, and highly sensitive, being capable of detecting mutations at the level of 0.1% of total molecules. Moreover, the reaction can be multiplex...