Isotopic compositions of U and Pb were determined for relict zircon inclusions recovered from Muong Nong-type tektites from the Australasian and North American strewn fields. These inclusions are generally opaque white with granular textures, probably representing mechanical disaggregation and/or local melting and recrystallization. All zircons have strongly discordant U–Pb isotopic ratios and ...

This paper presents U, Pb isotopic data of synthetic EARTHTIME solutions and natural reference materials together with suggestions how to ensure long-term intra- inter-laboratory reproducibility high-precision TIMS U–Pb geochronology.

Introduction: The age significance of isotope chro-nometers in shocked, but not totally molten, extrater-restrial materials is still a matter of debate [1–3]. Numerous isotopic data from different isotopic systems have been obtained for meteorites, but most meteorites with apparent shock ages do not show petrographic evidence of strong shock metamorphic overprint. Deutsh and Schärer [4] carried...

The anti-neoplastic effects of histone deacetylase inhibitors (HDACi), Trichostatin A (TSA) and 4-phenylbutyrate (4-PB) on the human glioblastoma cell lines GBM-29, U-343 MG and U-343 MGa Cl. 2:6 were investigated. TSA and 4-PB induced apoptosis in the three cell lines in a dose- and time-dependent manner. Whereas caspase-3 activation was detected in all three cell lines, U-343 MG cells were mo...

Geochronology and thermochronology on detrital material provides unique constraints on sedimentary provenance, depositional ages, and orogenic evolution of source terrains. In this paper we describe a method and case-studies of measurement of both U/Pb and (U-Th)/He ages on single crystals of zircon that improves the robustness of constraints in each of these areas by establishing both formatio...

Multi-step chemical abrasion thermal ionization mass spectrometry (CA-TIMS) methods were developed for monazite using six samples that vary in composition and age—Amelia, Jefferson County, Burke, Elk Mountain, 554 and Madagascar. To evaluate whether the multi-step CA-TIMS approach reveals complexities in either age or composition that might be masked by single-step analysis, this study presents...