BACKGROUND Cardiac magnetic resonance (CMR) is used in the diagnosis and risk stratification of hypertrophic cardiomyopathy (HCM) and can detect myocardial replacement fibrosis (anindependent predictor of adverse cardiac outcomes) using late gadolinium enhancement (LGE). METHODS We retrospectively analysed CMR studies carried out over a 2 year period identifying those which were diagnostic of...

A simplified dynamical system for tropical cyclone intensity prediction based on a logistic growth equation (LGE) is developed. The time tendency of the maximum sustained surface winds is proportional to the sum of two terms: a growth term and a term that limits the maximum wind to an upper bound. The maximum wind evolution over land is determined by an empirical inland wind decay formula. The ...

OBJECTIVE To evaluate the prognostic value of late gadolinium enhancement (LGE) in dilated cardiomyopathy (DCM) patients. METHODS We searched PubMed, MEDLINE, the Cochrane library and EMBASE databases from September to December 2012 in the Renmin Hospital of Wuhan University, Wuhan, China for studies of LGE in DCM patients. We extracted the clinical outcomes (all-cause mortality, cardiovascul...

Methods 47 (42 male, 42±8 years-old) consecutive patients (pts) with paroxysmal AF and indication to ablation were included. Exclusion criteria for CMR: non-sinus rhythm and general contra-indications. Before ablation all underwent CMR for left atrial angiography for CARTO mapping. Using CMR, the following variables were assessed: left ventricle (LV) and left atrium (LA) volumes and ejection fr...

We have studied the molecular identity of adult mouse SVZ cells in situ, and after isolation and expansion as neurospheres in vitro. The gene and protein expression patterns of the adult cells have been compared to that of the cells from the lateral ganglionic eminence (LGE), their putative embryonic counterparts. The LGE gives rise to both striatal projection neurons and olfactory bulb interne...

BACKGROUND This study sought to evaluate the relation between long-term segmental and global functional outcome after revascularisation in patients with chronic ischaemic left ventricular dysfunction (LVD) and baseline markers of viability: late gadolinium enhancement (LGE) transmurality and contractile reserve (CR). METHODS Forty-two patients with chronic ischaemic LVD underwent low-dose dob...

BACKGROUND Regional variability of longitudinal strain (LS) has been previously described with echocardiography in patients with cardiac amyloidosis (CA), however, the reason for this variability is not completely evident. We sought to describe regional patterns in LS using feature-tracking software applied to cardiovascular magnetic resonance (CMR) cine images in patients with CA, hypertrophic...

Cortical interneurons originate from subpallial precursors and migrate into the cortex during development. Using genetic lineage tracing in transgenic mice we examine the contribution of two germinal zones, the septum and the lateral ganglionic eminence/caudal ganglionic eminence (LGE/CGE) to interneurons of the cortex. We find that the septal neuroepithelium does not generate interneurons for ...

BACKGROUND Recent studies have demonstrated the significant prognostic value of stress cardiac magnetic resonance (CMR) myocardial perfusion imaging. Apart from characterizing reversible perfusion defect (RevPD) from flow-limiting coronary stenosis, CMR late gadolinium enhancement (LGE) imaging is currently the most sensitive method for detecting subendocardial infarction (MI). We therefore tes...

BACKGROUND Some patients may have normal wall motion after myocardial infarction. The aim of this study was to determine the prevalence and prognosis of patients with myocardial scar in the absence of abnormal wall motion. We studied patients with suspected or known coronary artery disease (CAD) who were referred for cardiovascular magnetic resonance (CMR) for the assessment of global and regio...