Valerian (Valeriana officinalis L.) is an important medicinal plant that is widely exploited for its roots and rhizomes which contain valepotriates and valerenic acids (with putative pharmacological activities). Thus root proliferation of valerian is very important. The aim of this study was to establish a practical tissue culture method for rapid and large-scale induction of V. officinalis L. ...

To investigate the method for quantitatively determining chlorogenic acid in Verbena officinalis L. extract; and to determine its content and in-vitro antibacterial activity. Cylinder-plate method and MIC assay were employed to compare the antibacterial activity between different concentrations of Verbena officinalis L. extracts; and to evaluate the antioxidant activity of various extracts in t...

The aim of the present study was to evaluate the central effects of the phytotherapeutic product-CPV (dry extract of Crataegus oxyacantha, Passiflora incarnata and Valeriana officinalis) in animals models. In order to investigate the psychopharmacological profile of CPV extract, an evaluation toward anxiolytic effect of this extract on the elevated plus-maze (EPM) was carried out. Other effects...

INTRODUCTION The rising trend to consume herbal products for the treatment and/or prevention of minor ailments together with their chemical and pharmacological complexity means there is an urgent need to develop new approaches to their quality and stability. OBJECTIVES This work looks at the application of one-dimensional diffusion-edited (1)H-NMR spectroscopy (1D DOSY) and (1)H-NMR with supp...

Several clinical studies have shown that valerian is effective in the treatment of insomnia, most often by reducing sleep latency. A double-blind, placebo-controlled trial compared a 400-mg aqueous extract of valerian and a commercial valerian/hops preparation with placebo of encapsulated brown sugar. A total of 128 volunteers completed a subjective study evaluating the effects of single doses ...

Ever since the discovery of the element iodine by Courtois (1) in 1812 and the first clinical uses of this substance in the treatment of goiter by Prout (2) in 1816 and by Coindet (3) in 1820, almost continuous researches on the relationship of iodine to thyroid function have been in progress. The greatest obstacle in the way of these investigations has been the lack of a reliable method for th...

In order to investigate essential oils with biological activity from local wild plants, two valerianaceous species, Nardostachys chinensis and Valeriana officinalis, were screened for their antimicrobial and antioxidant activity. The essential oils were obtained from the roots and rhizomes of the two plants by hydro-distillation, and were analyzed for their chemical composition by gas chromatog...