The present study investigated the current contamination status and evaluated several kinetic-related features of organochlorine pesticides (OCPs) and PCBs in human breast milk collected from northern Vietnam. The variation in the levels of these contaminants was found to be strongly associated with total lactation time and dietary habits. OCPs exhibited the characteristics of steadily declinin...

BACKGROUND Pregnant women are exposed to a mixture of endocrine disrupting chemicals (EDCs). Gestational EDC exposures may be associated with changes in fetal growth that elevates the risk for poor health later in life, but few studies have examined the health effects of simultaneous exposure to multiple chemicals. This study aimed to examine the association of gestational exposure to five chem...

Soil profiles were collected at a depth of 30 cm in ditch wetlands (DWs), riverine wetlands (RiWs) and reclaimed wetlands (ReWs) along a 100-year chronosequence of reclamation in the Pearl River Delta. In total, 16 OCPs were measured to investigate the effects of wetland reclamation and reclamation history on OCP levels. Our results showed that average ∑DDTs, HCB, MXC, and ∑OCPs were higher in ...

An increasing number of industrial, agricultural and commercial chemicals in the aquatic environment lead to various deleterious effects on organisms, which is becoming a serious global health concern. In this study, the Ames test and SOS/umu test were conducted to investigate the potential genotoxicity and mutagenicity caused by organic extracts from drinking water sources. Organic content of ...

Growing evidence indicates that exposure to organochlorine pesticides (OCPs) could increase non-Hodgkin lymphoma (NHL) risk. However, results from epidemiological studies investigating this association remain controversial. We thus conducted a meta-analysis to quantitatively evaluate the association between OCP exposure and NHL risk. Relevant publications were searched in PubMed, Web of Science...

OBJECTIVE To estimate the association of the estrogen and progestin potency of combined oral contraceptive pills (OCPs) with epithelial ovarian carcinoma risk. METHODS This population-based case-control study included 745 women with incident, histologically confirmed epithelial ovarian carcinoma and 943 controls, matched on age and ethnicity. Data were collected using a standard questionnaire...

Bone surfaces attract hematopoietic and nonhematopoietic cells, such as osteoclasts (OCs) and osteoblasts (OBs), and are targeted by bone metastatic cancers. However, the mechanisms guiding cells toward bone surfaces are essentially unknown. Here, we show that the Gαi protein-coupled receptor (GPCR) EBI2 is expressed in mouse monocyte/OC precursors (OCPs) and its oxysterol ligand 7α,25-dihydrox...

Abstract Trace residues of organochlorine pesticides (OCPs) in estuarine surface sediments were investigated at three protected wetlands southern Taiwan using high‐resolution gas chromatography/high‐resolution mass spectrometry (HRGC/HRMS) and chromatography‐electron capture detector (GC‐ECD). This study facilitates the development new strategies for investigating OCPs, particularly background ...

Objective. The capillary gas chromatographic method was introduced for determining organochlorine pesticide residues (OCPs) in traditional Chinese medicines: Gastrodia Tuber, Fructus Corni and Spica Prunellae. Methods. The organochlorine pesticides were extracted from herbs with mixed solvents (petroleum ether), cleaned up by concentrated HzSO4, and separated by capillary column with electron c...

Recent years have seen an upsurge of interest in developing low cost and reliable methods for the detection and precise determination of ultra-trace concentrations of persistent organic pollutants (POPs), because of their bioaccumulation, transformation and toxicity. Therefore, a comprehensive review with 108 references referring to the distribution, source, accumulation, transformation, types ...