BACKGROUND Exhaled nitric oxide levels are low in patients with cystic fibrosis (CF), despite the chronic inflammation present in the airways. This study aimed to determine whether levels of exhaled nitric oxide were reduced prior to the onset of respiratory symptoms in infants with CF. METHODS The levels of exhaled nitric oxide were measured using a chemiluminescence analyser in five infants...

BACKGROUND AND OBJECTIVES We investigated the effect of different breathing aids on ventilation distribution in healthy adults and subjects with cystic fibrosis (CF). METHODS In 11 healthy adults and 9 adults with CF electrical impedance tomography measurements were performed during spontaneous breathing, continuous positive airway pressure (CPAP) and positive expiratory pressure (PEP) therap...

OBJECTIVE To investigate whether transient-evoked and distortion-product (DP) otoacoustic emissions (OAEs) are more sensitive than pure-tone audiometry (PTA) in revealing gentamicin-induced ototoxicity in children with cystic fibrosis (CF). DESIGN Prospective case-control study. SETTING Tertiary referral audiologic center in conjunction with an academic pediatric CF unit. PARTICIPANTS The...

BACKGROUND Pulmonary function of children with cystic fibrosis (CF) and bronchopulmonary dysplasia (BPD) is similar at rest even though the mechanisms of injury differ. We sought to compare the peak exercise responses in children with BPD versus CF while controlling for pulmonary impairment, nutritional status, gender, age, height, and predicted forced expired volume in 1 second (approximately ...

Abstract Background The present study aimed to examine the biocontrol efficacy of 28 yeast isolates against Aspergillus niger , common pathogen onion black mold disease. antagonistic potential A. growth was investigated using a dual culture technique. Results Five isolates, including 8 and 11, showed highest inhibition effect on mycelial . Molecular analysis 16S RNA identified strains (AUN-AH14...

Cystic fibrosis (CF, OMIM 219700) is one of the most common severe hereditary diseases occurring in white populations. It is characterised by considerable heterogeneity in the mutational spectrum and a diverse phenotypic presentation, which justifies extensive studies on the correlation between the cystic fibrosis transmembrane regulator (CFTR) genotype and the CF phenotype. Genotype-phenotype ...