نتایج جستجو برای: روش dq
تعداد نتایج: 380188 فیلتر نتایج به سال:
For q any power of two, the dual Dq of the binary linear code spanned by the lines of the regular (q, q)-generalized quadrangle W(q) is shown to be a q-error correcting one-step completely orthogonalizable code of length q3 + q2 + q + 1. By a previous result (Bagchi and Sastry, 1987, Geom. Dedicata 22, 137-147), the rate of Dq is at least half in the limit as q ~ or. We also determine the full ...
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked endogenous class II molecules to study the interaction between the DR and DQ molecules and define the immunologic mechanisms in rheumatoid arthritis. Using collagen-induced arthritis (CIA) as an experimental mo...
The HLA system consists of a group of cell surface proteins encoded for by genes located on the short arm of chromosome 6. Since the discovery of this system in the 1950s, it has become clear that HLA molecules play an important role in controlling immune responses generated by the interaction of these proteins with foreign antigens. Humans have three class 1 HLA antigens (A, B, and C) that are...
The effect of recombinant human interferon gamma (IFN-gamma) on the induction of HLA class II (HLA-DR, -DP, -DQ) antigen expression on human corneal epithelial (HCE) cells was examined in different stages of culture. Primary cultures were established with limbal explants without endothelium. HCE cells in Stage 1 and Stage 2, with cells negative and positive for the 64K corneal keratin (the mark...
Civan and Sliepcevich [1, 2] suggested that special matrix solver should be developed to further reduce the computing effort in applying the differential quadrature (DQ) method for the Poisson and convection-diffusion equations. Therefore, the purpose of the present communication is to introduce and apply the Lyapunov formulation which can be solved much more efficiently than the Gaussian elimi...
In human type 1 diabetes (T1D) and in its murine model, the major histocompatibility complex (MHC) class II molecules, human leukocyte antigens (HLA)-DQ and -DR and their murine orthologues, IA and IE, are the major genetic determinants. In this report, we have ranked HLA class II molecule-associated T1D risk in a two-sided gradient from very high to very low. Very low risk corresponded to domi...
Three genome-wide association studies (GWAS) have been conducted on the genetic susceptibility of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), two of which consistently identified tagging single nucleotide polymorphisms (SNPs) around HLA-DQ/DR. In contrast, large multi-centre association studies between HBV genotype, mutations and the risk of HCC are relatively rare, and thei...
Knowledge of the binding repertoires and specificities of HLA-DQ molecules is somewhat limited and contradictory, partly because of the scarcity of reports addressing some of the most common molecules and possibly because of the diversity of the techniques used. In this paper, we report the development of high-throughput binding assays for the six most common DQ molecules in the general worldwi...
UNLABELLED Background and aim. Leukocyte antigen DQ (HLA-DQ) and interferon-λ4 (IFNL4) gene polymorphisms were associated with susceptibility to chronic hepatitis B and C virus infection. This study further confirmed that variants of these genes were associated with susceptibility and spontaneous clearance of HBV infection in a Chinese population. MATERIAL AND METHODS A total of 1,069 subjec...
BACKGROUND Ovarian cancer is one of the most lethal gynecological malignancies and the fifth leading cause of cancer deaths among women. The high mortality rate is largely attributed to its diagnosis in advanced stages. Poor prognosis of ovarian cancer is usually due to the lack of specific or effective screening and diagnostic methods for identifying early-stage disease. AIM Our study aimed ...
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