Restless leg syndrome (RLS) is a sensorimotor disorder. Clinical studies have implicated the dopaminergic system in RLS, while others have suggested that it is associated with insufficient levels of brain iron. To date, alterations in brain iron status have been demonstrated but, despite suggestions from the clinical literature, there have been no consistent findings documenting a dopaminergic ...

The Raman laser spectrometer (RLS) instrument onboard the Rosalind Franklin rover of ExoMars 2022 mission will analyze powdered samples on Mars to search for traces life. To prepare mission, RLS scientific team has developed Simulator (RLS Sim), a flexible model that operates similarly actual instrument, both in laboratory and field conditions, while also emulating operational constraints terms...

Objective. Restless leg syndrome (RLS) is a chronic distressing disease characterized by an urge to move the legs with an unpleasantsensation during periods of rest. The global prevalence estimates of RLS range from 2.5% to 15%. Method. This cross-sectional study was conducted at various hospitals in Karachi during August 13 to March 14. The visitors who had accompanied patients to Outpatient D...

INTRODUCTION AND OBJECTIVES Restless legs syndrome (RLS) is a type of neurological disorder which presents with an uncontrollable urge to move legs and arms. It commonly affects legs more than arms. Data regarding prevalence of restless legs syndrome in leprosy are sparse. The aims and objectives of the study were to find out the prevalence of RLS in people affected by leprosy and to determine ...

Restless legs syndrome (RLS) is a disease characterized by the presence of an urge to move the legs accompanied by unpleasant sensations in the legs. The symptoms appear or increase in the evening and during the night, they are provoked by rest, and are totally or partially relieved by moving the legs [1, 2] . Diagnosis of RLS is based solely on the presence of the abovementioned symptoms witho...

OBJECTIVE Restless legs syndrome (RLS) has been reported to be more prevalent in schizophrenic patients who take antipsychotics. The cause of RLS is unknown but associated with dopaminergic deficiency. Tyrosine hydroxylase (TH) is the enzyme responsible for catalyzing the conversion of L-tyrosine to DOPA. The purpose of this study is to determine whether the TH gene Val81Met polymorphism is ass...

Ramularia leaf spot (RLS), caused by the fungus Ramularia collo-cygni, is a serious, recently emerged disease of barley in Europe and other temperate regions. This study investigated the trade off between strong resistance to powdery mildew conferred by mlo mutant alleles and increased susceptibility to RLS. In field trials and seedling tests, the presence of mlo alleles increased severity of R...

BACKGROUND Recent studies have suggested a strong link between migraines and restless legs syndrome (RLS). It is possible that these disorders share a dopaminergic dysfunction in the hypothalamic A11 nucleus that contributes to this association. However, there have been no clinical studies to evaluate the effect of dopaminergic treatment on migraine symptoms in patients with concomitant migrain...

Study Question: Restless legs syndrome (RLS) is a common and often underestimated neurological disorder, with a prevalence ranging from approximately 2.5% to 10% in Western industrialised countries. The aim of this study was to summarise the research findings on the human and economic costs associated with RLS in populations without any co-morbidities or potentially confounding health condition...

Restless legs syndrome (RLS) and periodic limb movements in sleep (PLMS) are related conditions that often are comorbid. A diagnosis of RLS is made on the basis of patient complaints, and PLMS is diagnosed by polysomnography (PSG). Both RLS and PLMS are common in older adults, affecting 19% and 66% of elders, respectively. Although numerous studies have investigated other sleep disturbances (e....