The effects of adrenochrome, a metabolite of epinephrine (adrenaline), and 9,10-phenanthrenequinone (PQ), a component of diesel exhaust particles, on the stereoselective reduction of 4-benzoylpyridine (4-BP) were examined in pig heart cytosol. PQ was a potent inhibitor for the 4-BP reduction, while adrenochrome was a poor inhibitor. A similar result was observed in the effects of adrenochrome a...

UNLABELLED We have previously shown that paraquat (PQ)-induced oxidative stress causes dramatic damage in various human cell lines. Naringenin (NG) is an active flavanone, which has been reported to have beneficial bioactivities, including antioxidative, anti-inflammatory, and antitumorigenic activities, with a relatively low toxicity to normal cells. In this study, we intended to assess the cy...

Rats exposed to the quaternary herbicide paraquat (PQ) exhibit oxidative stress and lung irijury.'In the present study, we investigated the effect ofmultiple exposures to PQ on aerobic perfbrmance during progressive exercise on a treadmiU in rats. PQ was dissolved in saline (SAL) (1O mgfml) and administered intraperitoneally 7 mglkg body wt to Wistar rats (n = 5) once a week for one month, Cont...

Paraquat (PQ) poisoning remains a major public health concern in many countries. Extensive research has focused on finding early diagnostic biomarkers of acute PQ poisoning. In order to investigate the characterization of diagnostic biomarkers in PQ poisoning, we utilized proteomic analysis using serum from rats exposed to PQ, and we identified 8 differentially expressed proteins from over 500 ...

Environmental exposure to the oxidant-producing herbicide, paraquat (PQ) (1,1'-dimethyl-4,4'-bipyridinium dichloride) has long been implicated as a risk factor in Parkinson's disease (PD). PQ-induced oxidative stress has been exploited as a model to screen putative neuroprotective compounds employing Drosophila. In the present study, we investigated the prophylactic efficacy of Bacopa monnieri ...

Graphdiyne nanomaterials are low density and highly porous carbon-based two-dimensional (2D) materials, with outstanding application prospects for electronic energy storage/conversion systems. In two latest scientific advances, large-area pyrenyl graphdiyne (Pyr-GDY) pyrazinoquinoxaline (PQ-GDY) nanosheets have been successfully fabricated. As the first theoretical study, herein we conduct firs...

R. Hofer and A. Winterhof proved that the 2-adic complexity of two-prime (binary) generator period pq with two odd primes $$p\ne q$$ is close to its it can attain maximum in many cases. When applied producing quaternary sequences, we need determine 4-adic complexity. It there are only possible values for generator, which at least $$pq-1-\max \{\log _4(pq^2),\log _4(p^2q)\}$$ . Examples p q $$5\...

BACKGROUND The disarranged fat stripe of the pronator quadratus muscle (PQ) on radiographs (the PQ sign) is reported to be predictive of subtle bone fractures. This study aimed to report the results of magnetic resonance imaging (MRI) study in the patients in whom bone injury was not radiographically detected around the wrist joint, and the PQ was sonographically swollen following acute trauma....

The continuous infusion of taurine markedly protected against paraquat (PQ)-induced oliguria in beagles. Pharmacokinetic studies revealed that taurine infusion increased the blood concentration of PQ and reduced the net content in the kidney and, to a lesser extent, in the lung. The excretion of PQ into the urine was unaltered. The infusion of glycine did not have such effects.

The present study investigated the predictive values of urine paraquat (PQ) concentration, dose of poison, arterial blood lactate and Acute Physiology and Chronic Health Evaluation (APACHE) II score in the prognosis of patients with acute PQ poisoning. A total of 194 patients with acute PQ poisoning, hospitalized between April 2012 and January 2014 at the First Affiliated Hospital of P.R. China...