Source positioning close to the tumour in high dose rate (HDR) brachytherapy is not instantaneous. An increment of dose will be delivered during the movement of the source in the trajectory to its static position. This increment is the transit dose, often not taken into account in brachytherapeutic treatment planning. The transit dose depends on the prescribed dose, number of treatment fraction...

P"rpse: To investigate the clinical and histological toxicity of the exposure of the :rabbit cornea1 endothelium to anterior chamber injection of liposome-encapsulated 5-fluorouridine (LS-FUR) at concentrations of 1 mg/ml and 0.38 mg/ml and intravitreal injection of I.5FUR at 1 mg/ml. M*thOdS : A total of 12 New Zealand white rabbits were divided in three groups: A) Anterror chamber rnjectian o...

A comprehensive review for the in-air calibration of an Ir-192 high-dose-rate brachytherapy source in terms of air kerma strength (AKS) and reference air kerma rate (RAKR) using the Farmer chamber was conducted. The reviewed calibration methods include the National Physical Laboratory (NPL) calibration standard in the UK, the 7-distance technique with the standard calibration of the National In...

PURPOSE To observe the efficiency of reirradiation with high dose rate intraluminal brachytherapy in symptomatic palliation of recurrent endobronchial tumors. MATERIALS AND METHODS Between January 1994 and June 1998, 21 patients diagnosed with recurrent endobronchial tumors following external beam radiotherapy were treated palliatively with high dose rate intraluminal irradiation at Hacettepe...

The selection and use of any method to be used for radiography depends on a number of considerations, these in general being: a) The size, shape, orientation and distribution of imperfection in the weld. b) The dimensions, geometry and physical properties of the weld and material. c) The radiographic sensitivity required by the Standard, Code or Specification. d) Cost of radiography. e) The loc...

tope has recently been proposed as a hypothetical brachytherapy source due to its high specific activity, appropriate half-life (272 days) and medium energy photons (114.17 keV on average). In this study, Task Group No. 43 dosimetric parameters were calculated and reported for a hypothetical 57Co source. Material and methods: A hypothetical 57Co source was simulated in MCNPX, consisting of an a...

Dose distributions of (192)Ir HDR brachytherapy in phantoms simulating water, bone, lung tissue, water-lung and bone-lung interfaces using the Monte Carlo codes EGS4, FLUKA and MCNP4C are reported. Experiments were designed to gather point dose measurements to verify the Monte Carlo results using Gafchromic film, radiophotoluminescent glass dosimeter, solid water, bone, and lung phantom. The re...