background: this study investigated blackberry (persian mulberry) effects on apo a-i, apo b, high-sensitivity-c-reactive protein (hs-crp), and systolic blood pressure (sbp) and diastolic blood pressure (dbp) in dyslipidemic patients. materials and methods: in this 8-week randomized clinical trial, 72 dyslipidemic patients were randomly divided into two groups: intervention (300 ml/day blackberr...

Congenital generalized lipodystrophy is a rare inherited disease. One of its features is a disturbance in lipid metabolism characterized by hypercholesterolemia and hypertriglyceridemia. A brother and a sister with congenital generalized lipodystrophy, an 8-year old male and a 12-year old female were studied. The mother and a 6-year old brother were healthy. The genetic analysis of Sstl RFLP of...

Background: Thrombophilia has been viewed as a multigenic disorder rather than a monogenetic clinical phenotype and Apo E has been shown to play an important role in lipid metabolism in pregnancy. As individuals carrying the E4 allele of the ApoE gene have the highest risk for thrombosis, we evaluated the frequency of the Apo E4 genotype among women suffering from recurrent pregnancy loss. Mate...

Background. Besides their role in reverse cholesterol transport, HDL particles may affect the atherosclerotic process through the modulation of subclinical inflammation. HDL particles differ in size, composition, and, probably, anti-inflammatory properties. This hypothesis has never been explored in diabetic women, frequently having dysfunctional HDL. The potential relationship between lipid pr...

APO-B merupakan apolipoprotein terbesar dari fraksi Very Low Density Lipoprotein (VLDL). Hipertrigliseridemia membuat hati memproduksi lebih banyak VLDL dan LDL kaya trigliserida yang akan dihidrolisis untuk menghasilkan padat kecil (sd-LDL) melalui Cholesterol ester transfer protein (CETP) lipase hati. Sekitar 90% adalah LDL, rasio K-LDL/APO-B sebagai indikator partikel LDL. Penelitian ini dil...

Background: Systemic inflammation, limited mobility, and glucocorticoid treatment in idiopathic inflammatory myopathies (IIM) can have a negative impact on intermediate metabolic pathways, especially lipid metabolism. Objectives: The aim of this study was to assess the differences profile IIM patients healthy controls (HC) association with disease-specific features. Methods: 133 (106 females; m...

Indium is a heavy metal belonging to group IIIa. It is believed that indium may interfere with iron metabolism from the sites of absorption, transportation, utilization and storage in the cells. The present investigation was established to study and compare the binding of iron and indium to human apo-transferrin (apo-tf). Pure human apo-tf was used and the binding activity of iron and indium, a...