The effect of coniferyl alcohol as a precursor of flavonolignan biosynthesis on silymarin components production in Silybum marianum suspension culture was studied. Coniferyl alcohol showed the changes in silymarin complex production. Silydianin was detected mainly in the control samples of cultivated cells. A significant increase of silydianin was observed only after 72 h of the application of ...

background & aim: milk thistle [silybum marianum (l.) gaertn] is an annual or biennial plant, native to the mediterranean area, which has spread in north and south of iran. a fruit of milk thistle contains a relatively high amount (approx. 20%) of oil, which exhibits wound-healing, anti-burn, and hepatoprotective properties. experimental: in this research, a pot experiment was conducted usi...

the abilities of silybum marianum cell culture to biotransform benzaldehyde to benzyl alcohol in three culture systems were compared. callus cultures of silybum marianum were established from seedlings, and healthy suspensions and immobilized cultures grown on the murashige and skoog medium. s. marianum cells were immobilized in both agar beads and fiber cotton matrixes. benzaldehyde was fed to...

Objective: Biological verification of an eight-ingredient hepatoprotective recipe available in the Egyptian market was carried out followed by biologically guided reduction of non-essential ingredients aiming determination of the most potent formula containing the least number of ingredients to facilitate quality assessment procedure. Methods: Investigation of hepatoprotective effect afforded b...