OBJECTIVE To evaluate clinical value of oxidized lipoprotein(a) [ox-Lp(a)] levels. DESIGN AND METHODS Ox-Lp(a) were measured by 2 ELISAs using antibodies against ox-Lp(a) [ox-Lp(a)1] or oxidized low-density lipoprotein [ox-Lp(a)2], and studied in 161 acute coronary syndromes (ACS) patients, 114 stable coronary artery disease (CAD) and 100 control subjects. RESULTS Ox-Lp(a)1 was found relate...

BACKGROUND Lichen planus (LP) is a common inflammatory skin disease of unknown aetiology. Viral causes have been suggested. OBJECTIVES To find candidate viruses associated with LP. METHODS Lesional and nonlesional skin samples, peripheral blood mononuclear cells and serum were obtained from patients with LP. Ultrastructural, viral DNA, immunohistochemical and serological analyses were perfo...

BACKGROUND Increased serum lipoprotein(a) [Lp(a)] is an independent risk factor for atherosclerosis. We previously reported that aspirin reduced Lp(a) production by cultured hepatocytes via the reduction of apolipoprotein(a) [apo(a)] gene transcription. METHODS We evaluated both the effect of aspirin treatment (81 mg/day) on serum Lp(a) concentrations and the correlation between the degree of...

Lipoprotein(a) [Lp(a)] is a unique lipoprotein with controversial functions. Lp(a) contains apolipoprotein(a) [apo(a)] covalently attached to apolipoprotein B on the low-density lipoprotein (LDL) particle. The distribution of blood Lp(a) concentrations in several populations have been found to be skewed with Lp(a) being mostly present at low level (0-200 mg/L). A high Lp(a) concentration (great...

INTRODUCTION Early treatment of normal pressure hydrocephalus (NPH) yields better postoperative outcomes. Our current tests often fail to detect significant changes at early stages. We developed a new scoring system (LP log score) to determine if this tool is more sensitive in detecting clinical differences than current tests. MATERIAL AND METHODS Sixty-two consecutive new patients with suspe...

We include here several technical appendices. First, we formally derive the expressions for c l and b vote p that appear in section two of the paper. The next contains some details on the choice theoretic model underlying the standard topic model. The remainder contain the details for implementing the SFA model. A The Legislator and Proposal Intercepts from the Voting Model Let’s start with the...

Let ? be a weight function defined on locally compact group G, 1?p<+?, S?G and let us assume that for any s?S, the left translation operator Ts is continuous from weighted Lp-space Lp(G,?) into itself. For given set ??C, vector f?Lp(G,?) said to (?,S)-dense if {?Tsf:???,s?S} dense in Lp(G,?). In this paper, we characterize existence of vectors terms ?.

BACKGROUND Recent clinical studies showed that lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a predictor for incident atherosclerotic disease. We have previously shown that among the LDL subfractions, Lp-PLA(2) activity is preferentially associated with the atherogenic small, dense (sdLDL) particles in vitro. We investigated whether Lp-PLA(2) could be a marker of sdLDL in human plasm...

Pregnancy is associated with ventricular hypertrophy and volume overload. Here we investigated whether late pregnancy is associated with cardiac structural and hemodynamic changes, and if these changes are reversed postpartum. Female mice (C57BL/6) were used in nonpregnant diestrus (NP), late-pregnant (LP), or 7-day postpartum (PP7) stages. Echocardiography and cardiac catheterization were perf...