Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are inflammatory disorders caused by multiple factors. Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model. DSS induces in vivo but not in vitro intestinal inflammation. In addition, no DSS-associated molecule (free glucose, sodium sulfate solution, free dextran) induces...

BACKGROUND Individually tailored cancer treatment is essential to ensure optimal treatment and resource use. Treatments for incurable metastatic non-small cell lung cancer (NSCLC) are evolving rapidly, and decision support systems (DSS) for this patient population have been developed to balance benefits and harms for decision-making. The aim of this systematic review was to inventory DSS for st...

This study provides insight into the inconsistent findings on the impact of task complexity on performance by identifying the mediating role of task motivation in the effect of task complexity on DSS motivation and the interactive impact of DSS motivation and DSS use on performance. A research model is proposed to test the mediating and interaction hypotheses. One hundred participants use an ex...

OBJECTIVES To quantify the effect of a new continuous-care guideline (GL)-application engine, the Picard decision support system (DSS) engine, on the correctness and completeness of clinicians' decisions relative to an established clinical GL, and to assess the clinicians' attitudes towards a specific DSS. METHODS Thirty-six clinicians, including residents at different training levels and boa...

the development of a number of different rapid prototyping (rp) technologies with wide-ranging capabilities, features and applications has created the problem of selecting an appropriate rp system for engineering educational institutions as well as manufacturing organizations intending to adopt this new technology. this paper presents an rp decision support system (rp dss) for ranking and selec...

OBJECTIVES This study aimed to identify independent predictors of reoperation after successful resection of discrete subaortic stenosis (DSS). BACKGROUND Recurrence of DSS has been reported to range from 0% to 55% of patients. Factors associated with recurrence have not been adequately defined. METHODS Patients were included if they had a diagnosis of DSS, normal segmental cardiac anatomy, ...

Objectives The purposes of this study were to determine whether neoadjuvant or adjuvant radiotherapy affected disease-specific survival (DSS) in patients with rectal cancer and whether stratification by tumor stage affected the results. Results 55.5% patients had neoadjuvant-radiotherapy (NRT), and 18.3% patients had adjuvant- radiotherapy (ART). Multivariable models showed that treatment typ...

Since the early 1970s, decision support systems (DSS) technology and applications have evolved significantly. Many technological and organizational developments have exerted an impact on this evolution. DSS once utilized more limited database, modeling, and user interface functionality, but technological innovations have enabled far more powerful DSS functionality. DSS once supported individual...