So far, we primarily used voltage-controlled stimuli of varying strength and duration. Experiments with current-controlled pulses are underway. It is worth noting that while modellers prefer current-controlled pulses because they are easier to interpret biophysically, some of the best results in the field have been achieved using voltage-controlled stimuli. Real-world stimulus waveforms are nev...

BACKGROUND The standard method of assessment of platelet function is represented by light transmission aggregometry (LTA), performed in citrated platelet-rich plasma (PRP). With LTA, decrease and subsequent post-cardiopulmonary bypass (CPB) recovery of platelet function have been reported during cardiac surgery. Multiple electrode aggregometry (MEA) may be used as point-of-care method to monito...

Proinflammatory cytokine - interleukin 1β (IL-1β) plays an important role in stress reactions in the structures of limbic system. The impact of stress on IL-1β may depend on the ontogenetic age. The study examined the influence of acute and chronic exposure to forced swim (FS) or high-light open-field (HL-OF) stressors on neurons containing IL-1β. Double immunofluorescence staining was used to ...

2-Amino-3-methyl-9H-pyrido[2,3-b]indole (MeA C) is a proximate mutagenic and carcinogenic heterocyclic amine formed during ordinary cooking. In model systems, MeA C can be formed by pyrolyses of either tryptophan or proteins of animal or vegetable origin. In the present study, the in vivo metabolism of MeA C in rats was investigated. Rats were dosed with tritium-labeled MeA C, and urine and fec...

A correlation multi-variate analysis of variance (MANOVA) test to statistically analyze changing patterns of multi-electrode array (MEA) electrophysiology data is developed. The approach enables us not only to detect significant mean changes, but also significant correlation changes in response to external stimuli. Furthermore, a method to single out hot-spot variables in the MEA data both for ...

Mononethanolamine (MEA)-based absorption-stripping for CO2 capture is studied. Energy demands in this process are dominated by the stripping column. The shortest stripping line distance approach is used to determine minimum energy requirements for the MEA stripping column under various lean loadings. Simultaneous reaction and vapor-liquid equilibrium is assumed and modeled by the direct incorpo...

Alkyl derivatives of MEA are used in the production of surfactants, dyes, in the manufacture of drugs as a buffer substance and for the stabilization of emulsions, in the manufacture of herbicides, cosmetics, antihistamines, are also of practical interest [1]. It is widely known also as useful “acid” gases (H2S, CO2, SO2, etc.) as absorbents in the process of cleaning process for gases in oil r...