We present a new method for the a priori approximation of the order of magnitude of the entries in the LU factors of a matrix A ∈ Cn×n. We are also able to predict which permutation matrices will be chosen by partial pivoting or complete pivoting Gaussian elimination. Our method uses maxplus algebra and is based purely on the modulii of the entries in the matrix. This approximation can be used ...

BACKGROUND Some controversy exists as to the effects of endothelin (ET) receptor antagonism on long-term post-myocardial infarction (MI) evolution, particularly as it relates to the timing of the intervention after MI (<24 hours versus 10 days). METHODS AND RESULTS Sham rats and rats surviving an acute MI for >20 hours (n=301) were assigned to treatment with saline or the nonselective ET(A) a...

Patterns of human land use (LU) necessarily transform the land systems that sustain and contain them. Importantly, the impacts of such transformations are not isolated in space and time. LU management decisions that are made at a given geographic unit regularly impact both human and nonhuman well-being beyond the spatiotemporal boundaries of that unit. To superintend the conflicts that arise ou...

Migration of circulating leukocytes from the vasculature into the surrounding tissue is an important component of the inflammatory response. Among the cell surface molecules identified as contributing to leukocyte extravasation is VCAM-1, expressed on activated vascular endothelium, which participates in all stages of leukocyte-endothelial interaction by binding to leukocyte surface expressed i...

The Lutheran glycoprotein (Lu), also known as basal cell adhesion molecule (B-CAM), is an Ig superfamily (IgSF) transmembrane receptor for laminin α5. Although Lu is not present in normal hepatocytes, its expression is significantly increased in hepatocellular carcinoma (HCC). In this study, we isolated thirteen phage antibodies to Lu from a phage library of peripheral blood from HCC patients, ...

UNLABELLED Tumor targeting and therapeutic efficacy of (177)Lu-labeled monoclonal antibody (mAb) RS7 (antiepithelial glycoprotein-1) was evaluated in a human nonsmall cell lung carcinoma xenograft model. The potential of (177)Lu-labeled RS7 was compared with that of RS7 labeled with (90)Y and a residualizing form of (131)I. METHODS A 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid...