We read with interest the recent study of Gattoussi et al. investigating the association between vitreomacular adhesion (VMA) and AMD. The authors did not find any statistically significant associations of VMA with any stage of AMD. This result is in contrast to other previous studies that have found an association between VMA and exudative AMD, suggesting that VMA might be a risk factor for ch...

We read with interest the recent study of Gattoussi et al. investigating the association between vitreomacular adhesion (VMA) and AMD. The authors did not find any statistically significant associations of VMA with any stage of AMD. This result is in contrast to other previous studies that have found an association between VMA and exudative AMD, suggesting that VMA might be a risk factor for ch...

We read with interest the recent study of Gattoussi et al. investigating the association between vitreomacular adhesion (VMA) and AMD. The authors did not find any statistically significant associations of VMA with any stage of AMD. This result is in contrast to other previous studies that have found an association between VMA and exudative AMD, suggesting that VMA might be a risk factor for ch...

We read with interest the recent study of Gattoussi et al. investigating the association between vitreomacular adhesion (VMA) and AMD. The authors did not find any statistically significant associations of VMA with any stage of AMD. This result is in contrast to other previous studies that have found an association between VMA and exudative AMD, suggesting that VMA might be a risk factor for ch...

We read with interest the recent study of Gattoussi et al. investigating the association between vitreomacular adhesion (VMA) and AMD. The authors did not find any statistically significant associations of VMA with any stage of AMD. This result is in contrast to other previous studies that have found an association between VMA and exudative AMD, suggesting that VMA might be a risk factor for ch...

multi-drug therapy in high blood pressure is appreciated to achieve a normalblood pressure.a simple spectrophotometric method based on principal component analysis has been proposed for simultaneous determination of amlodipine (amd) and metoprolol(met) in pharmacutical preparations. calibration matrix contains 3.402 µgml -1 to 170.130 µgml -1 and from 13.060 µgml -1 to 65.3 µgml -1 amlodipine a...

Age-related macular degeneration (AMD) is a vision impairing disease of the central retina characterized by early and late forms in individuals older than 50 years of age. However, there is little knowledge to what extent also younger adults are affected. We have thus set out to estimate the prevalence of early AMD features and late AMD in a general adult population by acquiring color fundus im...

Age-related macular degeneration (AMD) causes severe vision loss in the elderly; early identification of AMD risk could help slow or prevent disease progression. Toward the discovery of AMD biomarkers, we quantified plasma protein N(epsilon)-carboxymethyllysine (CML) and pentosidine from 58 AMD and 32 control donors. CML and pentosidine are advanced glycation end products that are abundant in B...

Age-related macular degeneration (AMD) is the leading cause of vision loss in those over the age of 50 years in the developed countries. The number is expected to increase by ∼1.5 fold over the next ten years due to an increase in aging population. One of the main measures of AMD severity is the analysis of drusen, pigmentary abnormalities, geographic atrophy (GA) and choroidal neovascularizati...

Abbreviations Introduction 1. Functional aspects of drusen regression in AMD 1.1. Etiology and pathogenesis of AMD 1.2. Clinical manifestations of AMD 1.3. Drusen 1.4. Functional characteristics of the retina in aging and AMD 1.5. Fundus autofluorescence 1.6. Fundus autofluorescence imaging and its limitations 1.7. Fundus autofluorescence anomalies associated with AMD 1.8. Functional correlates...