OBJECTIVE To complete a first audit cycle of asthma care in Darley Dale after starting an asthma clinic. DESIGN Pre-clinic (1989) and post-clinic (1990) analysis of medical records of patients with asthma. SETTING A group practice in Derbyshire. PATIENTS 161 pre-clinic, 238 post-clinic patients with asthma. MAIN OUTCOME MEASURES Term "asthma" in the patient's computerised problem list, ...

238

OBJECTIVE Analysis of the contribution of genetic (single nucleotide polymorphisms (SNP) at position -238 and -308 of the tumor necrosis factor alpha (TNF-α) and -592 of the interleukin-10 (IL-10) promotor genes) and of classical factors (age, alcohol, immunodepression, antirretroviral therapy) on the risk of liver cirrhosis in human immunodeficiency (HIV)-hepatitis C (HCV) virus coinfected pat...

BACKGROUND Tumor necrosis factor-α (TNF-α) has been suggested to play a very important role in the development and progression of hepatocellular carcinoma (HCC). Many studies have identified the associations of TNF-α-308 and -238 polymorphisms with HCC risk, but the results remain controversial. AIM We conducted this meta-analysis to evaluate the associations between TNF-α-308 and -238 polymo...

Herpotrichiellaceae spp. are known to be opportunistic human pathogens. Here, we report the ~28.46-Mb draft genome of Herpotrichiellaceae sp. UM 238, isolated from human skin scraping. The UM 238 genome was found to contain many classes of protective genes that are responsible for fungal adaptation under adverse environmental conditions.