Listeria monocytogenes is a gram-positive bacterial pathogen that multiplies in the cytosol of host cells and spreads directly from cell to cell. During cell-to-cell spread, bacteria become temporarily confined to secondary vacuoles. The broad-range phospholipase C (PC-PLC) of L. monocytogenes contributes to bacterial escape from secondary vacuoles. PC-PLC requires cleavage of an N-terminal pro...

Phosphoinositide-specific phospholipase C (PLC) plays a pivotal role in the signal transduction of various cellular responses. However, although it is undeniably important that modulators of PLC activity be identified, no direct PLC activity modulator has been identified until now. In this study, by screening more than 10,000 different compounds in human neutrophils, we identified a compound th...

Myogenic tone is an intrinsic property of the vasculature that contributes to blood pressure control and tissue perfusion. Earlier investigations assigned a key role in myogenic tone to phospholipase C (PLC) and its products, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). Here, we used the PLC inhibitor, U-73122, and two other, specific inhibitors of PLC subtypes (PI-PLC and PC-PL...

many factors affect yield loss in wheat harvesting with a grain combine harvester and there is no mathematical model to describe the behavior of this complex system. thus in this study, a fuzzy logic controller (flc) was designed, implemented and tested for the automatic settings of cylinder speed, concave clearance, fan speed and forward speed of a model 955 john deere combine. first, the mech...

Acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) are two naturally occurring carnitine derivates formed by carnitine acetyltransferase. The beneficial cardiovascular effects of ALC and PLC have been extensively evaluated in animals and humans during the last 20 years. For instance, many clinical trials have suggested ALC and PLC as potential strategies in the management of peripheral ar...

The TrkB receptor tyrosine kinase and its ligand, BDNF, have an essential role in certain forms of synaptic plasticity. However, the downstream pathways required to mediate these functions are unknown. We have studied mice with a targeted mutation in either the Shc or the phospholipase Cgamma (PLCgamma) docking sites of TrkB (trkB(SHC/SHC) and trkB(PLC/PLC) mice). We found that hippocampal long...

Power line channel is the time-frequency variant channel with impulsive noise. Therefore, power line communication makes performance degradation due to time-frequency variant and impulsive noise. To overcome performance degradation, we consider the unitary signal constellation scheme and investigate the performance improvement of unitary matrix frequency modulated orthogonal frequencydivision m...

This paper deals with power line communication in vehicle (PLC). PLC is a very promising communication solution in order to offer future in-vehicle applications without increasing wiring harnesses. We join recent additional measurements which have been carried out using modified indoor PLC modems. These PLC modems are based on the two main technologies, HomePLUG AV and HDPLC. Index Terms HomePL...

A new Multiple-Input Single-Output Powerline Communications (MISO PLC) transmission scheme is proposed as an extension to the conventional Single-Input Single-Output (SISO) PLC transmission scheme to achieve high data rate with diversity. This scheme is called Enhanced-PLC scheme (EPLC). A Space-Time (ST) coding is employed at the transmitter terminal. In addition, a modified Maximum-Likelihood...