Hot spots with a large electric field enhancement usually come in small volumes, limiting their applications in surface-enhanced spectroscopy. Using a finite-difference time-domain method, we demonstrate that spiky nanoparticle dimers (SNPD) can provide hot spots with both large electric field enhancement and large volumes because of the pronounced lightning rod effect of spiky nanoparticles. W...

Many database optimization activities, such as prefetching, data clustering and partitioning, and buuer allocation, depend on the detection of hot spots in access patterns. While a database designer can in some cases use special knowledge about the data and the users to predict hot spots, in general one must use information about past activity to predict future activity. However, algorithms tha...

the broad consumption of antibiotics such as fluoroquinolones and the genetic adaption of opportunistic pathogenic bacteria including pseudomonas aeruginosa , has led to develop of floroquinolone-resistant strains of pseudomonas aeruginosa . thus, the aim of the present study is to reveal the types of hot spot mutations occurring in selected dna gyrase subunit a gene in fluoroquinolone-resistan...

[1] Recent observations of ridge bathymetry suggest magmatic segmentation at fastand intermediatespreading centers is linked to the migration of the spreading axis over the mantle. At fastand intermediatespreading centers, Carbotte et al. (2004) observed that leading segments, those that are offset in the direction of ridge migration, are typically shallower (interpreted to be magmatically robu...

In this paper we consider a Wi-Fi hot spot were M users are performing TCP downloads from Internet remote servers. Our study focuses on characterizing the way the TCP flow control mechanisms affect the MAC protocol operations, and identifying the main causes of the throughput limitations shown by the TCP traffic. In particular, we show that the TCP throughput is not limited by the collision eve...

It has been observed that AU-rich sequences form homologous recombination hot spots in brome mosaic virus (BMV), a tripartite positive-stranded RNA virus of plants (P. D. Nagy and J. J. Bujarski, J. Virol. 71:3799-3810, 1997). To study the effect of GC-rich sequences on the recombination hot spots, we inserted 30-nucleotide-long GC-rich sequences downstream of AU-rich homologous recombination h...

Shared bu€er switches do not su€er from head of line blocking which is a common problem in simple input bu€ering. Shared bu€er switches have previously been studied under uniform and unbalanced trac patterns. However, due to the complexity of the model, it was not possible to fully explore the performance of such a switch, in the presence of a single hot spot. In this paper, we develop a new m...