نتایج جستجو برای: آزمون پیری زودرس aat

تعداد نتایج: 125013  

2016
Doris R. Medina-Garin Aissata Dia Gabriel Bedubourg Xavier Deparis Franck Berger Remy Michel

CONTEXT Despite existing preventive measures, the number of acute acoustic trauma (AAT) cases reported to the French Military Epidemiological Surveillance System (MESS) remains high. AIMS The objective of this study was to describe AAT and the preventive measures already implemented. SUBJECTS AND METHODS We conducted a descriptive cross-sectional analysis of AAT using data from the MESS for...

Journal: :International journal of psychiatry in clinical practice 2007
Kazuhiko Iwahashi Chikako Waga Mitsuaki Ohta

Animal-assisted therapy (AAT) was developed to promote human social and emotional functioning as a day-care program for psychiatric patients. In this study, we determined which animals 481 schizophrenic patients liked and what they thought about AAT, using an original questionnaire. It was found that more than 80% of the present patients liked animals and that they thought contact with animals ...

2017
Ya-Ling Feng Yong-Xiang Yin Jian Ding Hua Yuan Lan Yang Jian-Juan Xu Ling-Qin Hu

This present study was designed to investigate the effects of alpha-1-antitrypsin (AAT) on oxidative stress in preeclampsia (PE) by regulating p38 mitogen-activated protein kinase (p38MAPK) signaling pathway. HTR8/SVneo cells were randomly assigned into normal, hypoxia/reoxygenation (H/R), HR + AAT and HR + siRNA-AAT groups. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western...

ژورنال: :مجله غدد درون ریز و متابولیسم ایران 0
دکتر مریم رزاقی آذر m razaghiazar aliasghar hospital, tehran,iran.تهران، خیابان دستگردی، بین نفت و مدرس، کد 19164، بیمارستان حضرت علی اصغر.

استفاده از آنالوگ های gnrh برای درمان بلوغ زودرس و اثر آن برای حفظ قد نهایی، پزشکان را بیش از پیش به درمان بلوغ زودرس ایدیوپاتیک ترغیب کرده است. در سال 1999 در یک مطالعه 20 دختر با نوع آهسته پیشرونده بلوغ زودرس با سن شروع 2/0±1/4 سال گزارش شدند که بدون هیچ درمانی قد نهایی طبیعی پیدا کرده بودند. سن شروع بلوغ بر اساس سن پیدایش علایم اولیه بلوغ در 95% اجتماع یا دو انحراف معیار زیر متوسط سن شروع بل...

2014
Ilaria Ferrarotti Tomás P Carroll Stefania Ottaviani Anna M Fra Geraldine O’Brien Kevin Molloy Luciano Corda Daniela Medicina David R Curran Noel G McElvaney Maurizio Luisetti

BACKGROUND Alpha-1 antitrypsin (AAT) is the most abundant circulating antiprotease and is a member of the serine protease inhibitor (SERPIN) superfamily. The gene encoding AAT is the highly polymorphic SERPINA1 gene, found at 14q32.1. Mutations in the SERPINA1 gene can lead to AAT deficiency (AATD) which is associated with a substantially increased risk of lung and liver disease. The most commo...

Journal: :Journal of Korean Medical Science 1991
W. S. Hong S. I. Hong

Serum levels of alpha-1-Antitrypsin(AAT) were determined in 42 patients with hepatocellular carcinoma(HCC), 5 patients with metastatic liver cancer from stomach adenocarcinoma, 10 patients with liver cirrhosis, 10 patients with chronic hepatitis, and 66 controls by rocket immunoelectrophoresis using rabbit antiserum. The mean level of serum AAT was 225.5 +/- 73.0 mg/dl in 66 controls. The serum...

2015
Ofer Guttman Gabriella S Freixo-Lima

The acute-phase protein α1-antirypsin (AAT) has recently been suggested to exert beneficial effects in various immune-associated pathologies, such as graftversus-host disease, rheumatoid arthritis, multiple sclerosis and allogeneic transplantation. These effects have been demonstrated to take place through direct immunomodulation of dendritic cells, macrophages, neutrophils and B cells, while a...

ژورنال: :دانشور پزشکی 0
شهناز مجرب shahnaz mojarab محمدرضا واعظ مهدوی mohammadreza vaezmahdavi تقی الطریحی taghi altarihi مهرداد روغنی mehrdad roghani سقراط فقیه زاده soghrat faghihzadeh مجید حسن پورعزتی majid hassanpour ezati

مقدمه و هدف : محرومیت و نابرابری های اجتماعی ارتباط تنگاتنگی با سطح سلامت جوامع و افراد دارد. نشان داده شده که بین فقر و نابرابری با بیماری و امید به زندگی رابطه معناداری وجود دارد. این که فقر و نابرابری از طریق کدام گروه از مکانیزم های بیولوژیک می تواند سبب بروز آثار پاتولوژیک شود و این که کدام یک از مکانیسم های مربوط به « شیوه زندگی» ، « فقر» ، ویا « استرس های اجتماعی » ، عامل ایجاد این آثار ...

Journal: :Frontiers in plant science 2016
Lin Cheng Hong-Yu Yuan Ren Ren Shi-Qi Zhao Ya-Peng Han Qi-Ying Zhou Dan-Xia Ke Ying-Xiang Wang Lei Wang

Amino acid transporters (AATs) play important roles in transporting amino acid across cellular membranes and are essential for plant growth and development. To date, the AAT gene family in soybean (Glycine max L.) has not been characterized. In this study, we identified 189 AAT genes from the entire soybean genomic sequence, and classified them into 12 distinct subfamilies based upon their sequ...

2013
Silvia Rossi Marco Bozzali Monica Bari Francesco Mori Valeria Studer Caterina Motta Fabio Buttari Mara Cercignani Paolo Gravina Nicolina Mastrangelo Maura Castelli Raffaele Mancino Carlo Nucci Fabrizio Sottile Sergio Bernardini Mauro Maccarrone Diego Centonze

Genetic ablation of type-1 cannabinoid receptors (CB1Rs) exacerbates the neurodegenerative damage of experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS). To address the role on CB1Rs in the pathophysiology of human MS, we first investigated the impact of AAT trinucleotide short tandem repeat polymorphism of CNR1 gene on CB1R cell expression, and secondly on th...

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