نتایج جستجو برای: β switching
تعداد نتایج: 248844 فیلتر نتایج به سال:
Task-induced deactivations within the brain's default mode network (DMN) are thought to reflect suppression of endogenous thought processes to support exogenous goal-directed task processes. Older adults are known to show reductions in deactivation of the DMN compared to younger adults. However, little is understood about the mechanisms contributing to functional dysregulation of the DMN in agi...
SNi-like mechanisms, which involve front-face leaving group departure and nucleophile approach, have been observed experimentally and computationally in chemical and enzymatic substitution at α-glycosyl electrophiles. Since SNi-like, SN1 and SN2 substitution pathways can be energetically comparable, engineered switching could be feasible. Here, engineering of Sulfolobus solfataricus β-glycosida...
فرض کنید m یک منیفلد هموار همبند باشد و α یک متریک ریمانی روی m باشد، در این صورت یک متریکراندرس روی m عبارت است از یک متریک فینسلر به فرم f =β + α که در آن β یک 1-فرمی هموار با طول کمتر از یک می باشد. در این پایان نامه ابتدا هندسه فینسلری متریک های راندرس چپ پایا و دو پایا روی گروه های لی مورد بررسی قرار می گیرند سپس ژئودزیک های متریک های فینسلری چپ پایا و دو پایا روی گروه های لی محاسه می...
A delayed fetal-to-adult hemoglobin (Hb) switch ameliorates the severity of β-thalassemia and sickle cell disease. The molecular mechanism underlying the epigenetic dysregulation of the switch is unclear. To explore the potential cis-variants responsible for the Hb switching, we systematically analyzed an 80-kb region spanning the β-globin cluster using capture-based next-generation sequencing ...
تاثیر مهندسی کانال و نواحی کناری بر کارکرد فرکانسی و سوییچینگ ترانزیستور نانوتیوب کربنی و ماسفت سیلیکنی دو گیتی مطالعه گردیده است. پارامترهای عملکرد مانند فرکانس قطع، سرعت سوییچینگ، مشخصه دوقطبی و نسبت جریان حالت روشن به خاموش محاسبه و بهینه سازی شده اند. به دلیل ایجاد رفتار الکترواستاتیکی مطلوب، اتصالات سورس و درین یک بعدی مورد استفاده قرار گرفته است. کاهش فرکانس قطع در اثر نفوذ تابع موج در اک...
in this paper, sufficient conditions are proposed to investigate the robust stability of arbitrary switched linear systems with uncertain parameters belongs to the known intervals. in addition, a method is then established to determine the maximum intervals of parameters' variations which guarantee robust exponential stability of uncertain switched linear systems under arbitrary switching. in t...
due to the high efficiency and low switching losses of resonant power convertors in comparison with switching convertors, nowadays there is a growing trend towards these convertors. however, because of the high frequency of switching in such convertors, it is quite difficult to present an efficient control method. in this paper, based on the state feedback method and using pole placement techni...
Anti-Diabetic Sulfonylurea Stimulates Insulin Secretion Independent of Plasma Membrane KATP Channels
Understanding mechanisms by which glibenclamide stimulates insulin release is important particularly given recent promising treatment by glibenclamide of permanent neonatal diabetic subjects. Anti-diabetic sulfonylureas are thought to stimulate insulin secretion solely by inhibiting their high affinity KATP channel receptors at the plasma membrane of β cells. This normally occurs during glucose...
On-off switching and molecular logic in fluorescent molecules are associated with what chemical inputs can do to the structure and dynamics of these molecules. Herein, we report the structure of a naphthalene derivative, the fashion of its binding to β-cyclodextrin and DNA, and the operation of logic possible using protons, cyclodextrin, and DNA as chemical inputs. The compound crystallizes out...
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