Human Interferon β (INF-β) is a member of cytokines family which different studies have shown its immunomodulatory and antiviral activities. In this study an expression vector was designed and constructed for expression of human INF-β-1b either in shake flasks and bench top bioreactor. The designed vector was constructed based upon pET-25b(+) with T7 promoter. Recombinant human beta interferon ...

fecl3.6h2o was used as an efficient catalyst for the synthesis of highly functionalized piperidines via a one-pot five-component reaction of aromatic amines, aromatic aldehydes and β-keto esters in etoh at room temperature. the remarkable advantages offered by this method are good yields, simple procedure, short reaction times, no need to column chromatography and easy work-up. the structures o...

background :    pseudomonas aeruginosa is a severe challenge for antimicrobial therapy, because of chromosomal mutations or exhibition of intrinsic resistance to various antimicrobial agents such as most β-lactams. we undertook this study to evaluate the existence of sme, aim and vim metallo-beta lactamases encoding genes among p. aeruginosa strains isolated from icu patients in al-zahra hospit...

background: &beta-thalassemia; is the most common monogenic disorder in human. the (ct) polymorphism at -158 upstream region of the &gammag-globin; gene and pharmacological factors such as hydroxyurea have been reported to influence &gamma-globin; gene expression and the severity of clinical symptoms of &beta-thalassemia.; methods: in the present study, 51 &beta-thalassemia; intermediate patie...

potent induction of fetal hemoglobin (hbf) production results in alleviating the complications of β-thalassemia and sickle cell disease (scd). hbf inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. janus kinase/signal transducer and activator of transcription (jak/stat), mitogen activated protein kinas (mapk) and phosphoinositide 3-kinase (pi3k) are con...

glipizide has been found to form inclusion complexes with β-cyclodextrin (β-cd) in solution and in solid state. the present study was undertaken to determine a suitable method for scaling up glipizide-β-cd inclusion complex formation and to evaluate the effect of some parameters on the efficiency of complexation. the solid inclusion complexes of glipizide and β-cd were prepared at a molar ratio...

During recent years, there was growing demand in using microalga valuable products such as β-carotene in health care. β-Carotene has anti-cancer and anti-aging properties for human. In Dunaliella salina cells, β-carotene has a major protecting role for biomolecules, when the production of reactive oxygen species elevated. In the present study, we investigated the influence of the four most effe...

β-N-acetylhexosaminidases have great potential in applied biocatalysis owing to their ability act on a wide range of natural and modified substrates. In this work, from four Penicillium crustosum strains (PcHex) were studied. The production showed the highest enzymatic activity culture medium after 11–14 days cultivation. specific isolated purified PcHex hydrolysis 4-nitrophenyl-N-acetyl-β-D-ga...

<p><span>The research purpose was to conduct an empirical investigation into students’ use behavior of e-learning tools during the COVID-19 pandemic, a case study higher educational institutions in Thailand. The applied UTAUT2 theoretical model. Primary data collected using structured questionnaire from total 1,493 students across learning Structural equation modelling (SEM) conduct...