Phenolic composition and biological activities of fruit extracts from Italian and Algerian Olea europaea L. cultivars were studied. Total phenolic and tannin contents were quantified in the extracts. Moreover 14 different phenolic compounds were identified, and their profiles showed remarkable quantitative differences among analysed extracts. Moreover antioxidant and enzymatic inhibition activi...

BACKGROUND The medicinal importance of a novel plant Olax nana Wall. ex Benth. (family: Olacaceae) was revealed for the first time via HPLC-DAD finger printing, qualitative phytochemical analysis, antioxidant, cholinesterase, and α-glucosidase inhibitory assays. METHODS The crude methanolic extract of O. nana (ON-Cr) was subjected to qualitative phytochemical analysis and HPLC-DAD finger prin...

background pompe disease is an inherited metabolic disorder characterized by α-glycosidase deficiency, which leads to lysosomal glycogen accumulation in many different tissues. the infantile form is the most severe with a rapidly fatal outcome, while the late onset form has a greater phenotypic variability, characterized by skeletal muscle dysfunction and early respiratory involvement. bone min...

The aim of this study was to examine the possible antioxidant and antidiabetic effects of the aqueous extracts of four Flemingia species in Taiwan. A number of methods were employed for this investigation, including ABTS radical monocation scavenging, FRAP (ferric reducing antioxidant power) method, DPPH (1, 1-diphenyl-2-picrylhydrazyl) radical scavenging, total polyphenol content, total flavon...

BACKGROUND The continuous search for new lead compounds as viable inhibitors of specific enzymes linked to carbohydrate metabolism has intensified. Cyperus esculentus L. is one of the therapeutically implicated botanicals against several degenerative diseases including diabetes mellitus. MATERIALS AND METHODS This study evaluated the antioxidant and mechanism(s) of inhibitory potential of aqu...

BACKGROUND The mechanism of hypoglycemic and hypolipidemic activities of Pyrus biossieriana Buhse leaf extract (PbBLE) and its phytochemical component arbutin, have not been well determined. The present study was performed to understand the hypoglycemic activity mechanisms of pbBLE and arbutin more clearly. METHODS In vitro enzymatic carbohydrate digestion with PbBLE and arbutin was assessed ...

a study of insect digestive enzymes makes sense given that the gut is the major interface between the insect and its environment. an understanding of gut and digestive enzyme function is essential when advanced methods of insect management such as application of enzyme inhibitors and transgenic plants are developed to control insect pests. the aim of the current research project was to study mi...

The Lauraceae genus Litsea includes many tree species with pharmacological capabilities, including anti-diabetic benefits. Five plant were tested for their activity on α-amylase and α-glucosidase. This study evaluated phytochemical composition, phenolic flavonoid levels, α-glucosidase inhibitor of elliptica, ferruginea, firma, garciae, sp. Phytochemical screening was performed using specific re...