reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methyl-imi...

In this edition of Blood, Bertaina et al report 3-year survival exceeding 90% by using haploidentical αβ+CD3+/CD19+-depleted allogeneic transplantation for children with nonmalignant disorders.

Polycyclic aromatic hydrocarbons (PAH) are ubiquitous persistent organic pollutants forming as byproducts in combustion processes. These compounds can become nitrated the environment even more toxic nitro derivatives. Both PAHs and nitro-PAHs accumulate soils which lead to pollution of vast areas arable land. The best means their elimination from is bioremediation that degradation by soil micro...

Some processes of heat and electrical charge transfer under relativistic conditions have been studied allowing for primordial substance anisotropy. In particular, electrical charge convection and conductivity were examined in the framework of 3-D and 4-D formalisms. Dependences were obtained in which the left-hand-sides and right-hand-sides transformed identically as v , с → where v was the vel...

This article presents a method to estimate dynamic compaction crater depth using empirical equations. As main reference, three physical model studies that used sand and clay soils were considered (Jafarzadeh in Proceedings of the international conference on performance-based design earthquake geotechnical engineering, pp 1–8, 2006; Arslan et al. ICE Ground Improv 11(2):61–66, 2007; Yuan Geotech...

It is well known that infiltration of pathogenic T-cells plays an important role in psoriasis pathogenesis. However, the antigen specificity of these activated T-cells is relatively unknown. Previous studies using T-cell receptor polymerase chain reaction technology (TCR-PCR) have suggested there are expanded T-cell receptor (TCR) clones in psoriatic skin, suggesting a response to an unknown ps...

During a search for immunomodulatory receptors in the chicken genome, we identified a previously cloned chicken sequence as CRTAM homologue by its overall identity and several conserved sequence features. For further characterization, we generated a CRTAM specific mab. No staining was detectable in freshly isolated cell preparations from thymus, bursa, caecal tonsils, spleen, blood and intestin...

BACKGROUND Women living in deprived neighborhoods are a risk group for overweight and obesity, particularly during the childbearing years. Several socio-demographic characteristics may compound this risk, but little is known about why this might be the case. Sedentary behaviors are emerging as a socio-demographically patterned risk factor for obesity. The purpose of the present study was to ass...