Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...

reaction of 5-phenyl tetrazole with ethyl chloroacetate to form ethyl (5-phenyl-1h-tetrazol-1-yl) acetate (1). compound 1 react with hydrazine hydrate in ethanol yield 2-(5-phenyl-1h-tetrazol-1-yl) acetohydrazide (2). the condensation of (2) with various aldehydes yield the corresponding substituted n'-[-arylidene]-2-(5-phenyl-1h-tetrazol-1-yl) acetohydrazide (3a- j). the compounds obtaine...

pathogenic infections and inflammation are very common ailments humans suffer. upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. in line with these developments the synthesis of n-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4h-1...

The rise of CuI-catalyzed click chemistry has initiated an increased demand for azido and alkyne derivatives of amino acid as precursors for the synthesis of clicked peptides. However, the use of azido and alkyne amino acids in peptide chemistry is complicated by their high cost. For this reason, we investigated the possibility of the in-house preparation of a set of five Fmoc azido amino acids...

In the asymmetric unit of the title polymeric complex, {[CuI(C(11)H(9)N(3))]·0.5CH(3)CN}(n), there are two Cu(I) atoms, two N-[(pyridin-2-yl-κN)methyl-idene]pyridin-3-amine (PyPy) ligands and two I atoms. Both Cu(I) atoms have a distorted tetra-hedral geometry, each being coordinated by one I atom, two N atoms of one PyPy ligand and one N atom from an adjacent PyPy ligand. In the crystal, infin...

I processi cooperativi prevedono l’esecuzione di attività da parte di entità differenti allo scopo di perseguire un obiettivo comune. Considerando il contesto dei distretti produttivi, attraverso il progetto VISPO si propone una serie di modelli abilitanti all’esecuzione dinamica di tali processi in cui le attività sono svolte da servizi. In questo contesto il carattere di dinamicità deriva dal...

The paper proposes an approach to representing and reasoning about spatial regions with undetermined boundaries, using an adaptation of`RCC-theory', a region-based system for representing qualitative spatial relations developed over the last few years (Randell, Cui and Cohn 1992, Cohn, Randell and Cui 1994). The approach proposed is referred to as thèegg-yolk' representation: a region with unde...

The corrections provided by Xie and Cui [Xie, F., Cui, W., in press. Cost range and network structures. Social Networks, 30] to one of the heorems provided by Doreian [Doreian, P., 2006. Actor network utilities and network evolution. Social Networks, 28, 137–164] are both necessary nd helpful. Accepting these corrections, and linking them more closely to the work of Hummon [Hummon, N.P., 2000. ...

In 2011, Cui and Cao proposed a secure anonymous key agreement for distributed networks, in which user collect other users’ identity of his own group to utilize them in communication and attacker can’t determine the real identity of user. However, the drawback of calculation consumption exists in the above protocol. In the paper, we adopt Elliptic Curve Cryptography (ECC) to reduce the computat...

The aim of the work. 1,2,4-triazole derivatives possess a wide range pharmacological activity, so they are used for development drugs and active pharmaceutical ingredients. Due to reactivity 1,2,4-triazoles there many options their further structural modification on different reaction centers. Therefore, work was obtain new S-substituted 1,2,4-triazole-3-thiols, study physicochemical parameters...