y 1970, several ultrastructural studies reported that different cell types contained thin filaments, 50 Å in diameter, which resembled the actin filaments seen in muscle cells. Similar filaments were also observed in the growing tips of axons, where they formed a network or mesh along the periphery. By analogy, most scientists assumed these actin-like filaments would also be involved in contrac...

ferred from the fact that other maintenance treatments such as biologics should be considered in refractory UC patients treated with high-dose corticosteroids. Mucosal healing (MH) is becoming more widely accepted as a relevant outcome marker for UC. In a Norwegian population-based cohort study examining effects between the presence or absence of MH and long-term outcomes, MH at 1 year was conf...

Extracellular-superoxide dismutase (EC-SOD) levels in sera divide into two discontinuous groups: a low-level group below 400 ng/ml and a high-level group above 400 ng/ml [Adachi, Nakamura, Yamada, Futenma, Kato and Hirano (1994) Clin. Chim. Acta 229, 123-131]. Molecular genetic studies have shown that the donors in the high-level group have a single base substitution generating the exchange of ...

As shown by Holtfreter (1944, 1945, 1947), the isolated presumptive ectoderm of Triturus torosus develops into a mass of epidermal cells when cultured in a physiological medium. However, if it is treated with injurious media such as acid, alkaline, or Ca-free solutions, or alcohol, and then cultured in a physiological medium, it differentiates neural structures and mesenchyme. These observation...

Laboratory magnetic reconnection experiments have been performed for nearly 20 years. Elegant experiments by Stenzel and Gekelman @R. L. Stenzel and W. Gekelman, Phys. Rev. Lett. 42, 1055 ~1979!; W. Gekelman and R. L. Stenzel, Phys. Rev. Lett. 54, 2414 ~1985!# focused on the measurement of field quantities with a single movable probe in a highly reproducible plasma. Observations included a very...

A 41-year-old female presented with a history of gradually increasing esotropia (ET) for 23 years. The best corrected visual acuity was 20/63 in both eyes. Refraction values were -18.50 (-1.00*55) in the right eye and -13.25 (-3.00*105) in the left eye. The axial length was measured as 29.35 mm for the right eye and 28.36 mm for the left eye. The patient's ocular motility was very restricted in...

We investigated the structures of wintertime lower troposphere in Seoul, South Korea on 17 and 18 January 2017 by performing 1 h interval radiosonde observation numerical simulations. In daytime January, height convective boundary layer (CBL) sharply quickly increased when residual became a part CBL. From afternoon moist air with clouds began to substantially intrude radiative heating/cooling w...