Biofilm formation is one of the most important virulence factors for Candida species. can be defined as a whole microbial community formed by microorganisms producing extracellular polymers and clustering in matrix (...)

Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib the first approved drug for treatment advanced HCC. Depression frequent in cancer patients. Moreover, sorafenib might exert depression as an adverse reaction and paroxetine, selective serotonin reuptake inhibitor, recommended pharmacotherapy. This study aimed to investigate potential synergistic effects paroxeti...

This study was designed for investigate of antioxidant, and anti-proliferative activities acetone, methanol water extracts different parts (fresh underground parts) Cyclamen cilicium extracts. The antioxidant were determined using DPPH, ABTS free radical scavenging activities. Anti-proliferative in Caco-2 colon cancer cells detected by XTT assay. determination contents evaluated total phenolics...

Kolorektal kanser, dünyada kanser ilişkili ölümlerin en yaygın dördüncü sebebidir. Erianin antioksidan ve anti-tümör etkilere sahip Dendrobium ekstraktından elde edilen yeni bir dibenzil bileşiğidir. Bu çalışmada, erianinin HT29 kolorektal hücreleri üzerine olan terapötik etkileri araştırılmıştır. Erianinin hücre canlılığı XTT test ile koloni oluşumu ise formasyonu değerlendirilmiştir. hücreler...

As an effort to search for new antiviral agents from traditional medicine, the hot water (HW) extract of twelve traditionally used medicinal plants in Taiwan was evaluated for their in vitro anti-herpes simplex viruses (HSV; including HSV-1 and HSV-2) and anti-adenoviruses (ADV; including ADV-3, ADV-8 and ADV-11) activities with a XTT-based colorimetric assay. Results showed that the tested HW ...

The purpose of the present in vitro study was to compare the cytotoxic effect of two commercially available brands of mineral trioxide cement (ProRoot MTA and MTA Angelus), modified zinc oxide-eugenol cement (SuperEBA) and resin-modified glass ionomer cement (Vitrebond) using rat pulp cells (RPC-C2A) and human lung fibroblasts (MRC-5). The cells were cultured in typical culture conditions and e...

The aim of this study was to investigate the ability of hinokitiol to inhibit the formation of Candida biofilms. Biofilm inhibition was evaluated by quantification of the biofilm metabolic activity with XTT assay. Hinokitiol efficiently prevented biofilm formation in both fluconazole-susceptible and fluconazole-resistant strains of Candida species. We determined the expression levels of specifi...

The rule-based programming paradigm is omnipresent in a number of engineering domains. However, there are some fundamental semantical differences between it, and classic programming approaches. No generic solution for using rules to model business logic in classic software has been provided so far. In this paper a new approach for Generalized Rule-based Programming (GREP) is given. It is based ...

Antifungal resistance has been associated with biofilm formation in many microorganisms, but not yet in Malassezia pachydermatis. This saprophytic yeast can cause otitis and dermatitis in dogs and has emerged as an important human pathogen, responsible for systemic infections in neonates in intensive care units. This study aims to evaluate the in vitro antifungal susceptibility of M. pachyderma...

BACKGROUND Caryocar brasiliense Camb (Pequi) is a typical Brazilian Cerrado fruit tree. Its fruit is used as a vitamin source for culinary purposes and as a source of oil for the manufacture of cosmetics. C. brasiliense supercritical CO2 extracts exhibit antimicrobial activity against the bacteria Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and also possess antioxidant a...