Septic arthritis of the sternoclavicular joint (SCJ) is a rare condition accounting for 0.5% of bone and joint infections. The majority of cases require joint resection and advancement flaps to provide coverage to the resulting wound defect. However, in the setting of an infected wound space, surgeons are often inclined to allow wound healing by secondary intention. Negative pressure wound ther...

UNLABELLED Surgical wound infection is a serious and potentially catastrophic complication after joint arthroplasty. Urinary tract infection is a common infection that creates a potential reservoir of resistant pathogens and increases patient morbidity. We asked whether treated preoperative and postoperative urinary tract infections are risk factors for deep joint infection. We examined the med...

OBJECTIVE This study aimed to determine the incidence of nosocomial infections, the risk factors and the impact of these infections on mortality among patients undergoing to cardiac surgery. METHODS Retrospective cohort study of 2060 consecutive patients from 2006 to 2012 at the Santa Casa de Misericórdia de Marília. RESULTS 351 nosocomial infections were diagnosed (17%), 227 non-surgical i...

IMPORTANCE Surgical site infections remain one of the most frequent complications following abdominal surgery and cause substantial costs, morbidity and mortality. OBJECTIVE To assess the effectiveness of wound edge protectors in open abdominal surgery in reducing surgical site infections. EVIDENCE REVIEW A systematic literature search was conducted according to a prespecified review protoc...

Surgical site infections (SSIs) are largely preventable but are one of the most common healthcare-associated infections and are increasingly becoming a national concern for all clinicians involved in surgical wound care (NICE, 2008). SSIs have a significant negative impact on NHS clinical and financial resources, reducing the quality of life for both the patient and carer, and have increasing a...

Elective surgery for colorectal cancer involves a semi-contaminated operation, with a 3% to 26% incidence of postoperative wound infection (1). Risk factors for postoperative wound infection include high body-mass index (BMI) (2, diabetes mellitus(3), body-weight loss(4), advanced age(5), smoking(6), blood transfusion(7), and high intraoperative blood loss (8). The development of wound infectio...

Reproducible experimental surgical-wound infections in mice for use in the evaluation of topical antibacterial agents are described. The experimental would was created on the backs of mice by means of a midline incision and was infected by means of cotton sutures monocontaminated with Staphylococcus aureus or Pseudomonas aeruginosa. The course of these wound infections was followed by quantitat...

OBJECTIVE To evaluate the results of negative-pressure wound therapy (NPWT) in the treatment of surgical spinal site infections. MATERIALS AND METHODS The use of NPWT in postoperative infections after dorsal spinal surgery (transforaminal lumbar interbody fusion plus posterior instrumentation) was studied retrospectively. From February 2011 to January 2012, six patients (females) out of 317 (...

Significance: More than 2 million eye injuries and infections occur each year in the United States that leave civilians and military members with reduced or complete vision loss due to the lack of effective therapeutics. Severe ocular injuries and infections occur in varied settings including the home, workplace, and battlefields. In this review, we discuss the potential of developing antimicro...