BACKGROUND Pathologic analysis of deep tissue obtained during debridement of venous ulcers is often unnoticed in its importance. We previously reported pathologic findings on 139 patients with venous ulcers. The objective of this study was to correlate the pathologic findings in venous ulcers with wound healing to establish a negative margin for debridement. STUDY DESIGN Consecutive patients ...

Restenosis is an adverse outcome of angioplasty, characterized by vascular smooth muscle cell (VSMC) hyperplasia. However, therapies targeting VSMC proliferation delay re-endothelialization, increasing the risk of thrombosis. Resveratrol (RESV) inhibits restenosis and promotes re-endothelialization after arterial injury, but in vitro studies assessing RESV-mediated effects on endothelial cell g...

BACKGROUND Wounds of the lower extremities are a significant public health problem, being severe and costly to treat. Adjunctive treatment with hyperbaric oxygenation (HBOT) has proven to be a useful and cost-effective means of treating ischemic wounds, mainly in diabetic patients. OBJECTIVES To describe patients with ischemic wounds treated at the Rambam and Elisha Hyperbaric Medical Center ...

- healing of surgical wounds and their complications such as infection or scar formation are of major concern in surgery. tissue glues are advanced to reduce these problems. in a prospective study, we have evaluated surgical wound healing in 76 patients whose surgical wounds were repaired by tissue glues (histoacryl). this study was performed in four leaching hospitals (sina, shariaty, shohada,...

OBJECTIVE To evaluate the characteristics and outcome of patients undergoing lower extremity amputation in Hong Kong. DESIGN Cohort study. SETTING University teaching hospital, Hong Kong. PARTICIPANTS. One hundred and eighty-four Chinese adults who underwent lower extremity amputation. MAIN OUTCOME MEASURES Demographic data of the cohort, wound complication and revision amputation rates, ...

RATIONALE Although numerous reconstruction protocols have been reported for lower leg trauma, those for distal leg trauma remain few. We present the case of a woman with an implant exposure wound, who was successfully treated through fat grafting, without major flap surgery. PATIENT CONCERNS An 83-year-old woman with an exposed implant in lower extremity received reconstruction surgery once a...

Acute compartment syndrome (ACS) is a serious complication of lower-extremity trauma caused by accidents or post-procedure complications. ACS is characterized by increased pressure within the compartment, resulting in reduced blood flow, tissue hypoxia, and tissue necrosis. Fasciotomies to relieve pressure and debridement of necrotic tissue comprise primary treatment. My purpose is to present i...

Currently, open fracture in lower extremity is a common trauma, which can easily form the skin defect. If the skin defect become an ulcer or ulcer like wound, the treatments will encounter a sticky situation that is hard to heal. Although skin flap grafting, tissue stretching and expansion can be available in this situation, however, they all have disadvantages, such as time consuming, costly, ...

A 62-year-old previously asymptomatic man was attended in the emergency room for anginal chest pain of 6 hours’ evolution. His medical history was remarkable for a combined aortic and mitral valve replacement 15 years previously for endocarditis (anticoagulation with acenocoumarol) and an aneurysm of the noncoronary sinus and ascending aorta, treated with an end-to-end anastomosis (Dacron graft...

The intense development of methods of physical medicine has been noted recently. The new methods are treatment methods, which in many cases allow a reduction of treatment time and positively influence the quality of life of patients undergoing treatment. This applies to illnesses and injuries of the locomotor system and diseases affecting soft tissues, as well as chronic wounds. This article di...