We developed a self-consistent screened-Korringa± Kohn± Rostoker (KKR) method in an ab initio tight-binding formulation. The reduction in numerical e€ ort in comparison with that required for the standard KKR method is achieved by the choice of a suitable reference system. Following the idea of Zeller et al. (1995, Phys. Rev. B, 52, 8807), reference systems with repulsive mu n-tin potentials o...

Confluent LLC-PKi cells express many characteristics of renal prox imal tubule epithelia. We report here the use of this cell line to investigate the possible mechanisms of m-diamminedichloroplatinum(II) (1)1)1')induced nephrotoxicity and diethyldithiocarbamate (DDTC) ameliora tion. Cells were exposed to platinum-based drug for l h and then incubated in drug-free medium until assayed. There was...

This investigationwas designedto determinewhether livertumorgrowthcan be preventedby localizedradioac tivfty through radioactive gold (198Au) infusion. Colloidal 198Auis phagocytosedby Kupifercells and emits I@-and a-radiation. Measurementof a-radiation showedmarked 198Auliver concentration. Liver chemistries, histology, and isolated hepatocyte function studies that measure [14C]acetateincorpor...

objective â  febrile convulsion (fc) is a common cause of seizure in young children, withâ an excellent prognosis. in addition to genetic predisposition and infections,fcs are generally thought to be induced by metabolic and elemental changesâ during fever such as zinc (zn) deficiency. regarding the high prevalence ofâ febrile convulsions and the role of zn deficiency, we investigated the role ...

Data defining the isolated effect of insulin on whole body protein and glucose metabolism in cancer patients are limited. Ten normal volun teers (controls), age 55 ±3 years (mean ±SEM); 8 cancer patients, age 61 ±3years, weight loss 2 ±1% (CANWL); and 8 cancer patients, age 55 ±2 years, weight loss 18 ±2% (CAWL), were studied in the postabsorptive state. Whole body leucine kinetics were d...

Populations enriched in proliferative, mucous goblet, and absorptive cells were isolated by a method of repeated time dissociation of the colonie mucosa from the adult rat. Five sequential cell suspensions were obtained by rotating the everted colon in 0.2% trypsin solution in Eagle's minimum essential medium at 30°for 20 min each time. Approximately 3.7 x 107 cells were obtained from each col...

Immunohistology for expression of the CD3f and CD3e chains in TIL was performed in 138 paraffin-embedded primary oral squamous cell carcinoma tissues and 10 nontumor, inflammatory lesion.s. Semiquantitative analysis of the staining intensity for ¿chainexpression and number of t chain expression-positive cells distinguished tumors with absent or low ^expression (42 of 132) from those with norma...

Objective—The aim of the study was to determine the prevalence of cryoglobulinaemia and its clinical features among â-thalassaemia patients. Methods—Eighty eight multitransfused â-thalassaemia patients were studied. They were physically examined and asked about the presence of cryoglobulinaemia related symptoms. Hepatitis C virus (HCV) serology, HCV-RNA, HCV subtypes, viraemia, serum ferritin, ...

Cytotoxic ether lipid analogues have been studied for their ability to inhibit growth factor-dependent |< ¡r'*| signaling in Swiss 3T3 fibroblasts. l -Octadecyl^-methyl-rac-glycero-S-phosphocholine (ET-18-OCH3) in hibited 4<<V+ uptake and inositol(l,4,5)trisphosphate-induced "Ça2* release in saponin permeabilized cells with concentration producing 50% inhibition values of 55 and 360 UM,respec...